Immune Dysfunctions and Immune-Based Therapeutic Interventions in Chronic Lymphocytic Leukemia

Immune Dysfunctions and Immune-Based Therapeutic Interventions in Chronic Lymphocytic Leukemia

Chronic lymphocytic leukemia (CLL) is a B-cell malignancy characterized by a wide range of tumor-induced alterations, which affect both the innate and adaptive arms of the immune response, and accumulate during disease progression. In recent years, the development of targeted therapies, such as the...

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Bibliographic Details
Main Authors: Valentina Griggio, Francesca Perutelli, Chiara Salvetti, Elia Boccellato, Mario Boccadoro, Candida Vitale, Marta Coscia
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Immunology
Subjects:
chronic lymphocytic leukemia
immune dysfunction
immunotherapy
immunomodulation
targeted therapy
cellular therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.594556/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.594556/full

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