| Summary: | Objectives: Cultural beliefs often affect people’s attitude toward mental illness and their help-seeking behavior. Belief in superstitious causes of mental illness can lead to seeking help from non-medical practitioners, which might hinder treatment. This study aimed to explore the perception of mental illness and help-seeking behavior among healthcare students. Methods: A cross-sectional study carried out on a sample of 400 randomly selected undergraduate health professional students in Riyadh. Data collection involved two self-administered questionnaires: the causes and treatment routes for a female vignette with psychosis and the General Health Questionnaire-28. Results: The mean age of participants was 20.9 years, and 68.2% were male. Although participants reported a lack of personal history of mental illness (81.9%), female participants were more likely to disclose psychological distress as measured by General Health Questionnaire-28 (67.6%). Mental illness (47.2%) was chosen as the main reason for the problem depicted by the female vignette. General Health Questionnaire-28 scores for “caseness” did not affect perception about psychosis versus non-caseness. Factor analysis produced four dimensions for causes of psychosis: “social,” “psychobiological,” “superstitious,” and “socially undesirable”; and two treatment routes: “clinical” versus “social interventions.” Male participants leaned toward social factors for the cause of psychosis and were more likely to endorse social interventions for treatment. Conclusion: Healthcare students in Riyadh remained supportive of a biomedical approach toward the causation and treatment of mental illness. The use of religious practices as an adjunct was apparent. Students, especially females, were prone to experience more psychological distress.
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