The Mechanisms and the Applications of Antibacterial Polymers in Surface Modification on Medical Devices
Medical device contamination caused by microbial pathogens such as bacteria and fungi has posed a severe threat to the patients’ health in hospitals. Due to the increasing resistance of pathogens to antibiotics, the efficacy of traditional antibiotics treatment is gradually decreasing for the infect...
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Frontiers Media S.A.
2020-11-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2020.00910/full |
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doaj-fc62fa942e804e3aba18c186a0bfa7702020-11-25T04:04:38ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852020-11-01810.3389/fbioe.2020.00910571162The Mechanisms and the Applications of Antibacterial Polymers in Surface Modification on Medical DevicesHaofeng Qiu0Zhangyong Si1Yang Luo2Peipei Feng3Xujin Wu4Wenjia Hou5Yabin Zhu6Mary B. Chan-Park7Long Xu8Dongmei Huang9School of Medicine, Ningbo University, Ningbo, ChinaSchool of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, SingaporeSchool of Medicine, Ningbo University, Ningbo, ChinaSchool of Medicine, Ningbo University, Ningbo, ChinaSchool of Medicine, Ningbo University, Ningbo, ChinaSchool of Medicine, Ningbo University, Ningbo, ChinaSchool of Medicine, Ningbo University, Ningbo, ChinaSchool of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, SingaporeFaculty of Materials Science and Chemical Engineering, Ningbo University, Ningbo, ChinaNingbo Baoting Biotechnology Co., Ltd., Ningbo, ChinaMedical device contamination caused by microbial pathogens such as bacteria and fungi has posed a severe threat to the patients’ health in hospitals. Due to the increasing resistance of pathogens to antibiotics, the efficacy of traditional antibiotics treatment is gradually decreasing for the infection treatment. Therefore, it is urgent to develop new antibacterial drugs to meet clinical or civilian needs. Antibacterial polymers have attracted the interests of researchers due to their unique bactericidal mechanism and excellent antibacterial effect. This article reviews the mechanism and advantages of antimicrobial polymers and the consideration for their translation. Their applications and advances in medical device surface coating were also reviewed. The information will provide a valuable reference to design and develop antibacterial devices that are resistant to pathogenic infections.https://www.frontiersin.org/articles/10.3389/fbioe.2020.00910/fullantibacterial polymermechanismsurface coatingmedical deviceantibacterial effect |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Haofeng Qiu Zhangyong Si Yang Luo Peipei Feng Xujin Wu Wenjia Hou Yabin Zhu Mary B. Chan-Park Long Xu Dongmei Huang |
| spellingShingle |
Haofeng Qiu Zhangyong Si Yang Luo Peipei Feng Xujin Wu Wenjia Hou Yabin Zhu Mary B. Chan-Park Long Xu Dongmei Huang The Mechanisms and the Applications of Antibacterial Polymers in Surface Modification on Medical Devices Frontiers in Bioengineering and Biotechnology antibacterial polymer mechanism surface coating medical device antibacterial effect |
| author_facet |
Haofeng Qiu Zhangyong Si Yang Luo Peipei Feng Xujin Wu Wenjia Hou Yabin Zhu Mary B. Chan-Park Long Xu Dongmei Huang |
| author_sort |
Haofeng Qiu |
| title |
The Mechanisms and the Applications of Antibacterial Polymers in Surface Modification on Medical Devices |
| title_short |
The Mechanisms and the Applications of Antibacterial Polymers in Surface Modification on Medical Devices |
| title_full |
The Mechanisms and the Applications of Antibacterial Polymers in Surface Modification on Medical Devices |
| title_fullStr |
The Mechanisms and the Applications of Antibacterial Polymers in Surface Modification on Medical Devices |
| title_full_unstemmed |
The Mechanisms and the Applications of Antibacterial Polymers in Surface Modification on Medical Devices |
| title_sort |
mechanisms and the applications of antibacterial polymers in surface modification on medical devices |
| publisher |
Frontiers Media S.A. |
| series |
Frontiers in Bioengineering and Biotechnology |
| issn |
2296-4185 |
| publishDate |
2020-11-01 |
| description |
Medical device contamination caused by microbial pathogens such as bacteria and fungi has posed a severe threat to the patients’ health in hospitals. Due to the increasing resistance of pathogens to antibiotics, the efficacy of traditional antibiotics treatment is gradually decreasing for the infection treatment. Therefore, it is urgent to develop new antibacterial drugs to meet clinical or civilian needs. Antibacterial polymers have attracted the interests of researchers due to their unique bactericidal mechanism and excellent antibacterial effect. This article reviews the mechanism and advantages of antimicrobial polymers and the consideration for their translation. Their applications and advances in medical device surface coating were also reviewed. The information will provide a valuable reference to design and develop antibacterial devices that are resistant to pathogenic infections. |
| topic |
antibacterial polymer mechanism surface coating medical device antibacterial effect |
| url |
https://www.frontiersin.org/articles/10.3389/fbioe.2020.00910/full |
| work_keys_str_mv |
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