Bacterial delivery of the anti-tumor azurin-like protein Laz to glioblastoma cells
Abstract Salmonella typhimurium VNP-20009 (VNP) is a non-pathogenic attenuated strain, which, as a facultative anaerobe, preferentially accumulates in hypoxic regions of solid tumors. Here, VNP was utilized as a delivery vehicle of the anti-tumor protein Lipidated azurin, Laz, which is produced by t...
Main Authors: | Manar Mansour, Shehab Ismail, Khaled Abou-Aisha |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2020-03-01
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Series: | AMB Express |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13568-020-00995-8 |
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