A novel antifungal is active against Candida albicans biofilms and inhibits mutagenic acetaldehyde production in vitro.
The ability of C. albicans to form biofilms is a major virulence factor and a challenge for management. This is evident in biofilm-associated chronic oral-oesophageal candidosis, which has been shown to be potentially carcinogenic in vivo. We have previously shown that most Candida spp. can produce...
Main Authors: | Mikko T Nieminen, Lily Novak-Frazer, Wilma Rautemaa, Ranjith Rajendran, Timo Sorsa, Gordon Ramage, Paul Bowyer, Riina Rautemaa |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4081779?pdf=render |
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