Peri-Implant Soft Tissue Management Through Use of Cultured Gingival Graft: A Case Report

• Main Authors: Mohammad Mohammadi, Rasool Mofid, Mohammad Ali Shokrgozar
• Format: Article
• Language: English
• Published: Tehran University of Medical Sciences 2011-05-01
• Series: Acta Medica Iranica
• Subjects: Tissue Engineering; Gingiva; Peri-Implant Soft Tissue; Attached Gingiva; Keratinized Gingiva
• Online Access: http://journals.tums.ac.ir/upload_files/pdf/18553.pdf

Tissue-engineered gingival graft was used for regenerating facial gingiva around an implant at lower left first premolar area with insufficient attached gingiva. Engineered gingival graft was produced by mixing 250 ml bovine skin collagen with 250 ml nutritional medium containing human gingival fibroblasts (2×105). 3 months post-surgery, there were gains in the attached gingiva compared to pre-surgery. The histological examination revealed a keratinized tissue on the treated site. Based on the result of this investigation, this graft was safe and capable of generating keratinized gingiva.