Microchannel network hydrogel induced ischemic blood perfusion connection

Microchannel network hydrogel induced ischemic blood perfusion connection

Restoration of blood flow to damaged sites has commonly involved treatment with pro-angiogenic molecules but these have undesired side effects. Here the authors present a microchannel-patterned gelatin hydrogel that is able to rescue mouse and porcine models of hindlimb ischemia.

Bibliographic Details
Main Authors: Jung Bok Lee, Dae-Hyun Kim, Jeong-Kee Yoon, Dan Bi Park, Hye-Seon Kim, Young Min Shin, Wooyeol Baek, Mi-Lan Kang, Hyun Jung Kim, Hak-Joon Sung
Format: Article
Language:English
Published: Nature Publishing Group 2020-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14480-0
Description
Summary:Restoration of blood flow to damaged sites has commonly involved treatment with pro-angiogenic molecules but these have undesired side effects. Here the authors present a microchannel-patterned gelatin hydrogel that is able to rescue mouse and porcine models of hindlimb ischemia.
ISSN:2041-1723

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