Ras and Rheb Signaling in Survival and Cell Death
One of the most obvious hallmarks of cancer is uncontrolled proliferation of cells partly due to independence of growth factor supply. A major component of mitogenic signaling is Ras, a small GTPase. It was the first identified human protooncogene and is known since more than three decades to promot...
Main Authors: | Rolf Heumann, Christian Herrmann, Raphael Stoll, Anja Ehrkamp |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-05-01
|
Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/5/2/639 |
Similar Items
-
Amino Acid-Mediated Intracellular Ca<sup>2+</sup> Rise Modulates mTORC1 by Regulating the TSC2-Rheb Axis through Ca<sup>2+</sup>/Calmodulin
by: Yuna Amemiya, et al.
Published: (2021-06-01) -
Molecular cloning and characterization of Rheb from white shrimp (Litopenaeus vannamei)
by: X Liu, et al.
Published: (2018-02-01) -
mTOR direct interactions with Rheb-GTPase and raptor: sub-cellular localization using fluorescence lifetime imaging
by: Yadav Rahul B, et al.
Published: (2013-01-01) -
Perspectives of RAS and RHEB GTPase Signaling Pathways in Regenerating Brain Neurons
by: Hendrik Schöneborn, et al.
Published: (2018-12-01) -
Ox-LDL-Induced MicroRNA-155 Promotes Autophagy in Human Endothelial Cells via Repressing the Rheb/ mTOR Pathway
by: Jinlin Lv, et al.
Published: (2017-10-01)