The role of matrix metalloproteinases and vascular grouth facrors in differentional diagnostic of prostate’s diseases

The aim of this study was to determine of TRF1, MMP-7, FLT-1, KDR and VEGF mRNA expression levels obtained from prostate biopsies samples of patients with benign prostatic hyperplasia, prostate cancer and healthy men without prostate pathology. It was demonstrated that detection of TRF1, FLT-1, KDR...

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Bibliographic Details
Main Authors: V P Avdoshin, S A Pulbere, A V Loktev, A I Glukhov
Format: Article
Language:English
Published: Peoples’ Friendship University of Russia (RUDN University) 2014-12-01
Series:RUDN Journal of Medicine
Subjects:
Online Access:http://journals.rudn.ru/medicine/article/view/3191
Description
Summary:The aim of this study was to determine of TRF1, MMP-7, FLT-1, KDR and VEGF mRNA expression levels obtained from prostate biopsies samples of patients with benign prostatic hyperplasia, prostate cancer and healthy men without prostate pathology. It was demonstrated that detection of TRF1, FLT-1, KDR and MMP-7 expression levels correlations and TRF1/MMP-7 index was criteria of different way for different prostate neoplasm diagnostics.
ISSN:2313-0245
2313-0261