Patients with encapsulating peritoneal sclerosis have increased peritoneal expression of connective tissue growth factor (CCN2), transforming growth factor-β1, and vascular endothelial growth factor.

Patients with encapsulating peritoneal sclerosis have increased peritoneal expression of connective tissue growth factor (CCN2), transforming growth factor-β1, and vascular endothelial growth factor.

<h4>Introduction</h4>Encapsulating peritoneal sclerosis (EPS) is a devastating complication of peritoneal dialysis (PD). The pathogenesis is not exactly known and no preventive strategy or targeted medical therapy is available. CCN2 has both pro-fibrotic and pro-angiogenic actions and ap...

Full description

Bibliographic Details
Main Authors: Alferso C Abrahams, Sayed M Habib, Amélie Dendooven, Bruce L Riser, Jan Willem van der Veer, Raechel J Toorop, Michiel G H Betjes, Marianne C Verhaar, Christopher J E Watson, Tri Q Nguyen, Walther H Boer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0112050

Similar Items

Similar Items