Fingolimod Alters Tissue Distribution and Cytokine Production of Human and Murine Innate Lymphoid Cells

Fingolimod Alters Tissue Distribution and Cytokine Production of Human and Murine Innate Lymphoid Cells

Sphingosine-1 phosphate receptor 1 (S1PR1) is expressed by lymphocytes and regulates their egress from secondary lymphoid organs. Innate lymphoid cell (ILC) family has been expanded with the discovery of group 1, 2 and 3 ILCs, namely ILC1, ILC2 and ILC3. ILC3 and ILC1 have remarkable similarity to C...

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Bibliographic Details
Main Authors: Ahmet Eken, Mehmet Fatih Yetkin, Alperen Vural, Fatma Zehra Okus, Serife Erdem, Zehra Busra Azizoglu, Yesim Haliloglu, Mustafa Cakir, Enes Mehmet Turkoglu, Omer Kilic, Irfan Kara, Hamiyet Dönmez Altuntaş, Mohamed Oukka, Mehmet Serdar Kutuk, Meral Mirza, Halit Canatan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
S1PR1
ILC3
ILC1
Fingolimod
FTY720
SEW2871
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00217/full

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