The Epigenetically-Regulated microRNA-378a Targets TGF-β2 in TGF-β1-Treated Hepatic Stellate Cells

The Epigenetically-Regulated microRNA-378a Targets TGF-β2 in TGF-β1-Treated Hepatic Stellate Cells

Background/Aims: In liver fibrosis, the activation of hepatic stellate cells (HSCs) is considered as a pivotal event. It is well known that transforming growth factor-β1 (TGF-β1) is the main stimuli factor responsible for HSC activation. microRNAs (miRNAs), regulating various biological processes, h...

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Bibliographic Details
Main Authors: Fujun Yu, Jianhuan Yang, Kate Huang, Xiaodong Pan, BiCheng Chen, Peihong Dong, Jianjian Zheng
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
TGF-β2
DNA methylation
MicroRNA-378a
Hepatic stellate cell
Online Access:http://www.karger.com/Article/FullText/452536

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