Inherited arrhythmia syndromes leading to sudden cardiac death in the young: A global update and an Indian perspective

• Main Authors: Priya Chockalingam, Arthur A. Wilde
• Format: Article
• Language: English
• Published: Elsevier 2014-01-01
• Series: Indian Heart Journal
• Subjects: Cardiac channelopathies; Family screening; Genetic testing; Inherited arrhythmias; Sudden cardiac death
• Online Access: http://www.sciencedirect.com/science/article/pii/S0019483213003611

Inherited primary arrhythmias, namely congenital long QT syndrome, Brugada syndrome and catecholaminergic polymorphic ventricular tachycardia, account for a significant proportion of sudden cardiac deaths in young and apparently healthy individuals. Genetic testing plays an integral role in the diagnosis, risk-stratification and treatment of probands and family members. It is increasingly obvious that collaborative efforts are required to understand and manage these relatively rare but potentially lethal diseases. This article aims to update readers on the recent developments in our knowledge of inherited arrhythmias and to lay the foundation for a national synergistic effort to characterize them in the Indian population.