The Supraspinally Mediated Analgesic Effects of Zonisamide in Mice After Peripheral Nerve Injury Are Independent of the Descending Monoaminergic System
We have previously demonstrated that the antiepileptic drug zonisamide supraspinally generates analgesic effects on thermal and mechanical hypersensitivity in mice after peripheral nerve injury. To further establish the neurochemical basis for the supraspinally mediated analgesic action of zonisamid...
Main Authors: | Mitsuo Tanabe, Yuichi Takeuchi, Hideki Ono |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2007-01-01
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Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319342318 |
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