IL-17A Can Promote Propionibacterium acnes-Induced Sarcoidosis-Like Granulomatosis in Mice

IL-17A Can Promote Propionibacterium acnes-Induced Sarcoidosis-Like Granulomatosis in Mice

The etiology of sarcoidosis is unknown. In this study, Propionibacterium acnes (PA) was used to induce sarcoidosis-like granulomatous inflammation in a mouse model. Wild-Type (WT) C57BL/6 mice were divided into three groups: (1) WT-PA group; (2) WT-PA + Incomplete Freund's Adjuvant (IFA) group;...

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Bibliographic Details
Main Authors: Jiacui Song, Mengmeng Zhao, Qiuhong Li, Liqin Lu, Ying Zhou, Yuan Zhang, Tao Chen, Danli Tang, Nianyu Zhou, Chengsheng Yin, Dong Weng, Huiping Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
Propionibacterium acnes
sarcoidosis
granuloma
IL-17A
mice
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01923/full

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