The predictive factor for conjunctival melanoma recurrence
Conjunctival melanoma potentially deadly tumor. While many cases of conjunctival melanoma appeared to be a recurrence, there is no valid data about parameters to predict the recurrence of this tumor. This study intended to evaluate whether histopathologic features can be used as a predictor for recu...
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doaj-fce6a3989e824a528bd72fb6c391a58e2020-11-25T01:46:29ZengUniversitas Gadjah MadaJournal of the Medical Sciences0126-13122356-39312019-09-0151410.19106/MedSci00510420190924885The predictive factor for conjunctival melanoma recurrenceAgus Supartoto0Melita Suwan Djaja1Datu Respatika2Muhammad Bayu Sasongko3Department of Ophthalmology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, YogyakartaDepartment of Ophthalmology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, YogyakartaDepartment of Ophthalmology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, YogyakartaDepartment of Ophthalmology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, YogyakartaConjunctival melanoma potentially deadly tumor. While many cases of conjunctival melanoma appeared to be a recurrence, there is no valid data about parameters to predict the recurrence of this tumor. This study intended to evaluate whether histopathologic features can be used as a predictor for recurrence in conjunctival melanoma. This was a retrospective study, involving patients with conjunctival melanoma by the year 2013-1017 in Dr. Sardjito General Hospital and Dr. Yap Eye Hospital, Yogyakarta. Patient’s characteristic was determined by age, sex, laterality, tumor size, tumor location, histopathological dominancy, MMC application, recurrence, and metastases. Sixteen cases were found: male (62.5%) and female (37.5%). Age from 5-79 years, mean was 56.19 years. Tumor location was in bulbar in 11 patients (68.7%), palpebral in 5 patients (31.3%).There was significant association between metastasis and the tumor recurrence (OR 13.0; 95% CI 1.9-85.4; p = 0.007). A favorable trend of association was also found between location and the recurrence of melanoma (OR 15.0; 95% CI 0.9-228.8; p = 0.06). In summary, our study showed that the patients that developing distant metastasis were at a greater risk for tumor recurrence.https://jurnal.ugm.ac.id/bik/article/view/44642conjunctival melanoma - recurrence - histopathology- epithelioid- spindle- mixed |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Agus Supartoto Melita Suwan Djaja Datu Respatika Muhammad Bayu Sasongko |
spellingShingle |
Agus Supartoto Melita Suwan Djaja Datu Respatika Muhammad Bayu Sasongko The predictive factor for conjunctival melanoma recurrence Journal of the Medical Sciences conjunctival melanoma - recurrence - histopathology- epithelioid- spindle- mixed |
author_facet |
Agus Supartoto Melita Suwan Djaja Datu Respatika Muhammad Bayu Sasongko |
author_sort |
Agus Supartoto |
title |
The predictive factor for conjunctival melanoma recurrence |
title_short |
The predictive factor for conjunctival melanoma recurrence |
title_full |
The predictive factor for conjunctival melanoma recurrence |
title_fullStr |
The predictive factor for conjunctival melanoma recurrence |
title_full_unstemmed |
The predictive factor for conjunctival melanoma recurrence |
title_sort |
predictive factor for conjunctival melanoma recurrence |
publisher |
Universitas Gadjah Mada |
series |
Journal of the Medical Sciences |
issn |
0126-1312 2356-3931 |
publishDate |
2019-09-01 |
description |
Conjunctival melanoma potentially deadly tumor. While many cases of conjunctival melanoma appeared to be a recurrence, there is no valid data about parameters to predict the recurrence of this tumor. This study intended to evaluate whether histopathologic features can be used as a predictor for recurrence in conjunctival melanoma. This was a retrospective study, involving patients with conjunctival melanoma by the year 2013-1017 in Dr. Sardjito General Hospital and Dr. Yap Eye Hospital, Yogyakarta. Patient’s characteristic was determined by age, sex, laterality, tumor size, tumor location, histopathological dominancy, MMC application, recurrence, and metastases. Sixteen cases were found: male (62.5%) and female (37.5%). Age from 5-79 years, mean was 56.19 years. Tumor location was in bulbar in 11 patients (68.7%), palpebral in 5 patients (31.3%).There was significant association between metastasis and the tumor recurrence (OR 13.0; 95% CI 1.9-85.4; p = 0.007). A favorable trend of association was also found between location and the recurrence of melanoma (OR 15.0; 95% CI 0.9-228.8; p = 0.06). In summary, our study showed that the patients that developing distant metastasis were at a greater risk for tumor recurrence. |
topic |
conjunctival melanoma - recurrence - histopathology- epithelioid- spindle- mixed |
url |
https://jurnal.ugm.ac.id/bik/article/view/44642 |
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