Transcriptional Coactivator TAZ Negatively Regulates Tumor Suppressor p53 Activity and Cellular Senescence

Transcriptional Coactivator TAZ Negatively Regulates Tumor Suppressor p53 Activity and Cellular Senescence

Transcriptional coactivator with a PDZ-binding motif (TAZ) is one of the mammalian orthologs of <i>Drosophila</i> Yorkie, a transcriptional coactivator of the Hippo pathway. TAZ has been suggested to function as a regulator that modulates the expression of cell proliferation and anti-apo...

Full description

Bibliographic Details
Main Authors: Chiharu Miyajima, Yuki Kawarada, Yasumichi Inoue, Chiaki Suzuki, Kana Mitamura, Daisuke Morishita, Nobumichi Ohoka, Takeshi Imamura, Hidetoshi Hayashi
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
cellular senescence
oncogene
p300
p53
taz
Online Access:https://www.mdpi.com/2073-4409/9/1/171

Similar Items

Similar Items