Calcium depletion destabilises kinetochore fibres by the removal of CENP-F from the kinetochore

Calcium depletion destabilises kinetochore fibres by the removal of CENP-F from the kinetochore

Abstract The attachment of spindle fibres to the kinetochore is an important process that ensures successful completion of the cell division. The Ca2+ concentration increases during the mitotic phase and contributes microtubule stability. However, its role in the spindle organisation in mitotic cell...

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Bibliographic Details
Main Authors: Rinyaporn Phengchat, Hideaki Takata, Susumu Uchiyama, Kiichi Fukui
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07777-6

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