Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance

The mucosal barriers are very sensitive to pathogenic infection, thereby assuming the capacity of the mucosal immune system to induce protective immunity to harmful antigens and tolerance against harmless substances. This review provides current information about mechanisms of induction of mucosal...

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Main Authors: Dimitry A Chistiakov, Yuri V Bobryshev, Emil eKozarov, Igor A Sobenin, Alexander Nikolaevich Orekhov
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00781/full
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spelling doaj-fd2751c70276470d8ec5b31c87b286572020-11-24T22:54:15ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2015-01-01510.3389/fmicb.2014.00781121721Intestinal mucosal tolerance and impact of gut microbiota to mucosal toleranceDimitry A Chistiakov0Yuri V Bobryshev1Emil eKozarov2Igor A Sobenin3Alexander Nikolaevich Orekhov4Pirogov Russian State Medical UniversityUniversity of New South Wales and University of Western SydneyColumbia UniversityInstitute of General Pathology and Pathophysiology, Russian Academy of SciencesInstitute of General Pathology and Pathophysiology, Russian Academy of SciencesThe mucosal barriers are very sensitive to pathogenic infection, thereby assuming the capacity of the mucosal immune system to induce protective immunity to harmful antigens and tolerance against harmless substances. This review provides current information about mechanisms of induction of mucosal tolerance and about impact of gut microbiota to mucosal tolerance.http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00781/fullImmune Systemtoleranceintestinal microbiotamicrofloraHarmful antigens
collection DOAJ
language English
format Article
sources DOAJ
author Dimitry A Chistiakov
Yuri V Bobryshev
Emil eKozarov
Igor A Sobenin
Alexander Nikolaevich Orekhov
spellingShingle Dimitry A Chistiakov
Yuri V Bobryshev
Emil eKozarov
Igor A Sobenin
Alexander Nikolaevich Orekhov
Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance
Frontiers in Microbiology
Immune System
tolerance
intestinal microbiota
microflora
Harmful antigens
author_facet Dimitry A Chistiakov
Yuri V Bobryshev
Emil eKozarov
Igor A Sobenin
Alexander Nikolaevich Orekhov
author_sort Dimitry A Chistiakov
title Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance
title_short Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance
title_full Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance
title_fullStr Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance
title_full_unstemmed Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance
title_sort intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance
publisher Frontiers Media S.A.
series Frontiers in Microbiology
issn 1664-302X
publishDate 2015-01-01
description The mucosal barriers are very sensitive to pathogenic infection, thereby assuming the capacity of the mucosal immune system to induce protective immunity to harmful antigens and tolerance against harmless substances. This review provides current information about mechanisms of induction of mucosal tolerance and about impact of gut microbiota to mucosal tolerance.
topic Immune System
tolerance
intestinal microbiota
microflora
Harmful antigens
url http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00781/full
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AT yurivbobryshev intestinalmucosaltoleranceandimpactofgutmicrobiotatomucosaltolerance
AT emilekozarov intestinalmucosaltoleranceandimpactofgutmicrobiotatomucosaltolerance
AT igorasobenin intestinalmucosaltoleranceandimpactofgutmicrobiotatomucosaltolerance
AT alexandernikolaevichorekhov intestinalmucosaltoleranceandimpactofgutmicrobiotatomucosaltolerance
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