Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance
The mucosal barriers are very sensitive to pathogenic infection, thereby assuming the capacity of the mucosal immune system to induce protective immunity to harmful antigens and tolerance against harmless substances. This review provides current information about mechanisms of induction of mucosal...
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doaj-fd2751c70276470d8ec5b31c87b286572020-11-24T22:54:15ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2015-01-01510.3389/fmicb.2014.00781121721Intestinal mucosal tolerance and impact of gut microbiota to mucosal toleranceDimitry A Chistiakov0Yuri V Bobryshev1Emil eKozarov2Igor A Sobenin3Alexander Nikolaevich Orekhov4Pirogov Russian State Medical UniversityUniversity of New South Wales and University of Western SydneyColumbia UniversityInstitute of General Pathology and Pathophysiology, Russian Academy of SciencesInstitute of General Pathology and Pathophysiology, Russian Academy of SciencesThe mucosal barriers are very sensitive to pathogenic infection, thereby assuming the capacity of the mucosal immune system to induce protective immunity to harmful antigens and tolerance against harmless substances. This review provides current information about mechanisms of induction of mucosal tolerance and about impact of gut microbiota to mucosal tolerance.http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00781/fullImmune Systemtoleranceintestinal microbiotamicrofloraHarmful antigens |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Dimitry A Chistiakov Yuri V Bobryshev Emil eKozarov Igor A Sobenin Alexander Nikolaevich Orekhov |
spellingShingle |
Dimitry A Chistiakov Yuri V Bobryshev Emil eKozarov Igor A Sobenin Alexander Nikolaevich Orekhov Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance Frontiers in Microbiology Immune System tolerance intestinal microbiota microflora Harmful antigens |
author_facet |
Dimitry A Chistiakov Yuri V Bobryshev Emil eKozarov Igor A Sobenin Alexander Nikolaevich Orekhov |
author_sort |
Dimitry A Chistiakov |
title |
Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance |
title_short |
Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance |
title_full |
Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance |
title_fullStr |
Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance |
title_full_unstemmed |
Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance |
title_sort |
intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Microbiology |
issn |
1664-302X |
publishDate |
2015-01-01 |
description |
The mucosal barriers are very sensitive to pathogenic infection, thereby assuming the capacity of the mucosal immune system to induce protective immunity to harmful antigens and tolerance against harmless substances. This review provides current information about mechanisms of induction of mucosal tolerance and about impact of gut microbiota to mucosal tolerance. |
topic |
Immune System tolerance intestinal microbiota microflora Harmful antigens |
url |
http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00781/full |
work_keys_str_mv |
AT dimitryachistiakov intestinalmucosaltoleranceandimpactofgutmicrobiotatomucosaltolerance AT yurivbobryshev intestinalmucosaltoleranceandimpactofgutmicrobiotatomucosaltolerance AT emilekozarov intestinalmucosaltoleranceandimpactofgutmicrobiotatomucosaltolerance AT igorasobenin intestinalmucosaltoleranceandimpactofgutmicrobiotatomucosaltolerance AT alexandernikolaevichorekhov intestinalmucosaltoleranceandimpactofgutmicrobiotatomucosaltolerance |
_version_ |
1725661123137503232 |