Bifosfonat Kullanımına Bağlı Olarak Maksillada Kemik Nekrozu Oluşumu: Bir Olgu Sunumu

• Main Authors: Adnan Ozturk, Kaan Orhan, Durmus Ilker Gorur, Aysegul Mine Tuzuner Oncul, sila sahin
• Format: Article
• Language: English
• Published: Cumhuriyet University 2011-01-01
• Series: Cumhuriyet Dental Journal
• Online Access: http://dergi.cumhuriyet.edu.tr/ojs/index.php/dishekimligi/article/view/686

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mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} --> <!--[endif] --><!--[if gte mso 9]><xml> <o:shapedefaults v:ext="edit" spidmax="1026" /> </xml><![endif]--><!--[if gte mso 9]><xml> <o:shapelayout v:ext="edit"> <o:idmap v:ext="edit" data="1" /> </o:shapelayout></xml><![endif]--> <p class="MsoNormal" style="margin-bottom: 3pt; text-align: justify; line-height: 13pt; page-break-after: avoid;"><strong><span style="font-size: 10pt; letter-spacing: -0.4pt;">Amaç: </span></strong><span style="font-size: 10pt; letter-spacing: -0.4pt;">Bifosfonatlar, metastatik kemik kanserlerin önlenmesinde ve osteopörözün tedavisinde kullanılmaktadır. </span><span style="font-size: 10pt; letter-spacing: -0.2pt;">İntravenöz (i.v) bifosfonat (pamidronat, zoledronat)</span><span style="font-size: 10pt; letter-spacing: -0.4pt;"> tedavisine bağlı olarak çene kemiklerinde osteonekroz gelişmektedir. Bu vaka raporu ile kliniğimize başvuran hastanın tedavisi sunulmuştur.</span></p> <p class="MsoNormal" style="margin-bottom: 3pt; text-align: justify; line-height: 13pt;"><strong><span style="font-size: 10pt;"><span> </span>Vaka Raporu: </span></strong><span style="font-size: 10pt;">Kliniğimize başvuran 51 yaşındaki kadın hastada, uzun süreli intravenöz bifosfonat kullanımına bağlı sol maksilla molar bölgesinde asemptomatik osteonekroz görülmüştür. Hastaya gerekli debridman, sekestrasyon ve hiperbarik oksijen tedavisi uygulanmıştır. Hasta belirli aralıklarla takip edilmektedir.</span></p> <p class="MsoNormal" style="margin-bottom: 3pt; text-align: justify; line-height: 13pt;"><strong><span style="font-size: 10pt; letter-spacing: -0.2pt;"><span> </span>Sonuç: </span></strong><span style="font-size: 10pt; letter-spacing: -0.2pt;">Bifosfonat kullanımına bağlı oluşan osteonekroz, i.v. bifosfonat kullanımının artmasına bağlı olarak daha sık görülmektedir. Bu nedenle bifosfonat tedavisi görecek olan hastaların oluşabilecek komplikasyonların engellenmesi amacıyla, tedavi öncesinde diş hekimine yönlendirilip, tüm dental tedavilerinin yapılması önerilmektedir. </span></p>