Diffusion-Weighted Magnetic Resonance Imaging Value in the Detection and Differentiation of Bone Tumors and Tumor-Like Lesions

• Main Authors: Mostafa Emara, Ayman Nada, Maged Hawana, Mohamed Elazab, Ahmed Mohamed Shokry
• Format: Article
• Language: English
• Published: KARE Publishing 2019-05-01
• Series: Erciyes Medical Journal
• Subjects: magnetic resonance imaging (mri); diffusion-weighted imaging (dwi); apparent diffusion coefficient (adc); bone tumors; benign; malignant; tumor like
• Online Access: https://jag.journalagent.com/z4/download_fulltext.asp?pdir=erciyesmedj&un=EMJ-68878

Objective: The aim of this study was to evaluate the ability of diffusion-weighted magnetic resonance imaging (MRI) and its corresponding apparent diffusion coefficient (ADC) values in the detection, characterization, and discrimination between different types of bony lesions. Materials and Methods: Patients were evaluated by conventional and diffusion-weighted MR images. Diffusion was carried out using the b values of 0, 500, and 1000, and then the ADCs were generated. Results: The average ADC value of benign lesions was approximately 1.84×10–3 mm2/s+-0.33, while that of malignant lesions was approximately 1.17×10–3 mm2/s+-0.44; p<0.001. The receiver operating characteristic (ROC) curve analysis produced a cut-off value for the detection of malignancy of 1.47×10–3 mm2/s with 89.5% specificity and 79.5% sensitivity. Conclusion: Diffusion-weighted imaging combined with ADC values is considered a useful tool that can be added to the conventional MRI sequences for detection, differentiation, and characterization of different bony lesions.