Co-Expression Effect of SLC7A5/SLC3A2 to Predict Response to Endocrine Therapy in Oestrogen-Receptor-Positive Breast Cancer

Co-Expression Effect of SLC7A5/SLC3A2 to Predict Response to Endocrine Therapy in Oestrogen-Receptor-Positive Breast Cancer

The majority of breast cancers are oestrogen-receptor-positive (ER+) and are subject to endocrine therapy; however, an unpredictable subgroup of patients will develop resistance to endocrine therapy. The SLC7A5/SLC3A2 complex is a major route for the transport of large neutral essential amino acids...

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Bibliographic Details
Main Authors: Lutfi H. Alfarsi, Rokaya El-Ansari, Madeleine L. Craze, Brendah K. Masisi, Omar J. Mohammed, Ian O. Ellis, Emad A. Rakha, Andrew R. Green
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
breast cancer
oestrogen receptor
endocrine resistance
slc7a5
slc3a2
Online Access:https://www.mdpi.com/1422-0067/21/4/1407

Internet

https://www.mdpi.com/1422-0067/21/4/1407

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