Spreading and Imbibition of Vesicle Dispersion Droplets on Porous Substrates
Vesicles have recently found widespread use in applications such as conditioning of textiles, paper and hair, as well as transdermal drug delivery. The mode of treatment in several such cases involves the application of droplets of aqueous dispersions of vesicles onto dry porous substrates like pape...
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doaj-fd4d881770464354a4a0c3f72f827ea12020-11-25T02:22:45ZengMDPI AGColloids and Interfaces2504-53772019-07-01335310.3390/colloids3030053colloids3030053Spreading and Imbibition of Vesicle Dispersion Droplets on Porous SubstratesAbhijeet Kumar0Jochen Kleinen1Joachim Venzmer2Anna Trybala3Victor Starov4Tatiana Gambaryan-Roisman5Institute of Technical Thermodynamics, TU Darmstadt, 64287 Darmstadt, GermanyResearch Interfacial Technology, Evonik Nutrition & Care GmbH, 45127 Essen, GermanyResearch Interfacial Technology, Evonik Nutrition & Care GmbH, 45127 Essen, GermanyDepartment of Chemical Engineering, Loughborough University, Loughborough, LE11 3TU, UKDepartment of Chemical Engineering, Loughborough University, Loughborough, LE11 3TU, UKInstitute of Technical Thermodynamics, TU Darmstadt, 64287 Darmstadt, GermanyVesicles have recently found widespread use in applications such as conditioning of textiles, paper and hair, as well as transdermal drug delivery. The mode of treatment in several such cases involves the application of droplets of aqueous dispersions of vesicles onto dry porous substrates like paper and textiles. One of the factors which affects the performance of such treatments is the rate at which the droplets spread and imbibe on the porous substrate. Depending upon the specific purpose of the treatment either a fast or slow droplet spreading kinetics could be desired. Therefore, it is important to have a good understanding of the droplet spreading process and the factors which influence it. In this work, an experimental investigation of the simultaneous spreading and imbibition of vesicle dispersion droplets on cellulose filter papers is carried out. Two different types of vesicles which are composed of similar lipid molecules but exhibit contrasting lipid bilayer phase behavior are used. Two different grades of filter papers with comparable porosities but different thicknesses are used as porous substrate. It is found that the droplet spreading behavior is of the “complete wetting” type on the thicker porous substrate, whereas it is of the “partial wetting” type on the thinner substrate. Furthermore, it is observed that the spreading of droplets containing vesicles with liquid-crystalline phase bilayers occurs faster than that of vesicles with solid-gel phase bilayers. The secondary radial penetration which commences after the initial droplet spreading is complete is also investigated and discussed.https://www.mdpi.com/2504-5377/3/3/53vesicleswettingimbibition |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Abhijeet Kumar Jochen Kleinen Joachim Venzmer Anna Trybala Victor Starov Tatiana Gambaryan-Roisman |
spellingShingle |
Abhijeet Kumar Jochen Kleinen Joachim Venzmer Anna Trybala Victor Starov Tatiana Gambaryan-Roisman Spreading and Imbibition of Vesicle Dispersion Droplets on Porous Substrates Colloids and Interfaces vesicles wetting imbibition |
author_facet |
Abhijeet Kumar Jochen Kleinen Joachim Venzmer Anna Trybala Victor Starov Tatiana Gambaryan-Roisman |
author_sort |
Abhijeet Kumar |
title |
Spreading and Imbibition of Vesicle Dispersion Droplets on Porous Substrates |
title_short |
Spreading and Imbibition of Vesicle Dispersion Droplets on Porous Substrates |
title_full |
Spreading and Imbibition of Vesicle Dispersion Droplets on Porous Substrates |
title_fullStr |
Spreading and Imbibition of Vesicle Dispersion Droplets on Porous Substrates |
title_full_unstemmed |
Spreading and Imbibition of Vesicle Dispersion Droplets on Porous Substrates |
title_sort |
spreading and imbibition of vesicle dispersion droplets on porous substrates |
publisher |
MDPI AG |
series |
Colloids and Interfaces |
issn |
2504-5377 |
publishDate |
2019-07-01 |
description |
Vesicles have recently found widespread use in applications such as conditioning of textiles, paper and hair, as well as transdermal drug delivery. The mode of treatment in several such cases involves the application of droplets of aqueous dispersions of vesicles onto dry porous substrates like paper and textiles. One of the factors which affects the performance of such treatments is the rate at which the droplets spread and imbibe on the porous substrate. Depending upon the specific purpose of the treatment either a fast or slow droplet spreading kinetics could be desired. Therefore, it is important to have a good understanding of the droplet spreading process and the factors which influence it. In this work, an experimental investigation of the simultaneous spreading and imbibition of vesicle dispersion droplets on cellulose filter papers is carried out. Two different types of vesicles which are composed of similar lipid molecules but exhibit contrasting lipid bilayer phase behavior are used. Two different grades of filter papers with comparable porosities but different thicknesses are used as porous substrate. It is found that the droplet spreading behavior is of the “complete wetting” type on the thicker porous substrate, whereas it is of the “partial wetting” type on the thinner substrate. Furthermore, it is observed that the spreading of droplets containing vesicles with liquid-crystalline phase bilayers occurs faster than that of vesicles with solid-gel phase bilayers. The secondary radial penetration which commences after the initial droplet spreading is complete is also investigated and discussed. |
topic |
vesicles wetting imbibition |
url |
https://www.mdpi.com/2504-5377/3/3/53 |
work_keys_str_mv |
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