Dietary Antiplatelets: A New Perspective on the Health Benefits of the Water-Soluble Tomato Concentrate Fruitflow<sup>®</sup>
Our understanding of platelet functionality has undergone a sea change in the last decade. No longer are platelets viewed simply as regulators of haemostasis; they are now acknowledged to be pivotal in coordinating the inflammatory and immune responses. This expanded role for platelets brings new op...
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2021-06-01
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doaj-fd4dd7bf3ef345179ec9aceb9f2042f72021-07-23T13:58:15ZengMDPI AGNutrients2072-66432021-06-01132184218410.3390/nu13072184Dietary Antiplatelets: A New Perspective on the Health Benefits of the Water-Soluble Tomato Concentrate Fruitflow<sup>®</sup>Niamh O’Kennedy0Ruedi Duss1Asim K Duttaroy2Provexis PLC, c/o The University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen AB25 2ZD, UKDSM Nutritional Products Ltd., 4002 Basel, SwitzerlandDepartment of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, 0315 Oslo, NorwayOur understanding of platelet functionality has undergone a sea change in the last decade. No longer are platelets viewed simply as regulators of haemostasis; they are now acknowledged to be pivotal in coordinating the inflammatory and immune responses. This expanded role for platelets brings new opportunities for controlling a range of health conditions, targeting platelet activation and their interactions with other vascular cells. Antiplatelet drugs may be of wider utility than ever expected but often cause platelet suppression too strong to be used out of clinical settings. Dietary antiplatelets represent a nutritional approach that can be efficacious while safe for general use. In this review, we discuss potential new uses for dietary antiplatelets outside the field of cardiovascular health, with specific reference to the water-soluble tomato extract Fruitflow<sup>®</sup>. Its uses in different aspects of inflammation and immune function are discussed, highlighting exercise-induced inflammation, mediating the effects of air pollution, and controlling thrombotic aspects of the immune response. Potential future developments in women’s health, erectile dysfunction, and the allergic response indicate how broad the utility of dietary antiplatelets can be.https://www.mdpi.com/2072-6643/13/7/2184platelet functionplatelet activationplatelet hyperactivityplatelet-leukocyte aggregatesinflammationimmunothrombosis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Niamh O’Kennedy Ruedi Duss Asim K Duttaroy |
spellingShingle |
Niamh O’Kennedy Ruedi Duss Asim K Duttaroy Dietary Antiplatelets: A New Perspective on the Health Benefits of the Water-Soluble Tomato Concentrate Fruitflow<sup>®</sup> Nutrients platelet function platelet activation platelet hyperactivity platelet-leukocyte aggregates inflammation immunothrombosis |
author_facet |
Niamh O’Kennedy Ruedi Duss Asim K Duttaroy |
author_sort |
Niamh O’Kennedy |
title |
Dietary Antiplatelets: A New Perspective on the Health Benefits of the Water-Soluble Tomato Concentrate Fruitflow<sup>®</sup> |
title_short |
Dietary Antiplatelets: A New Perspective on the Health Benefits of the Water-Soluble Tomato Concentrate Fruitflow<sup>®</sup> |
title_full |
Dietary Antiplatelets: A New Perspective on the Health Benefits of the Water-Soluble Tomato Concentrate Fruitflow<sup>®</sup> |
title_fullStr |
Dietary Antiplatelets: A New Perspective on the Health Benefits of the Water-Soluble Tomato Concentrate Fruitflow<sup>®</sup> |
title_full_unstemmed |
Dietary Antiplatelets: A New Perspective on the Health Benefits of the Water-Soluble Tomato Concentrate Fruitflow<sup>®</sup> |
title_sort |
dietary antiplatelets: a new perspective on the health benefits of the water-soluble tomato concentrate fruitflow<sup>®</sup> |
publisher |
MDPI AG |
series |
Nutrients |
issn |
2072-6643 |
publishDate |
2021-06-01 |
description |
Our understanding of platelet functionality has undergone a sea change in the last decade. No longer are platelets viewed simply as regulators of haemostasis; they are now acknowledged to be pivotal in coordinating the inflammatory and immune responses. This expanded role for platelets brings new opportunities for controlling a range of health conditions, targeting platelet activation and their interactions with other vascular cells. Antiplatelet drugs may be of wider utility than ever expected but often cause platelet suppression too strong to be used out of clinical settings. Dietary antiplatelets represent a nutritional approach that can be efficacious while safe for general use. In this review, we discuss potential new uses for dietary antiplatelets outside the field of cardiovascular health, with specific reference to the water-soluble tomato extract Fruitflow<sup>®</sup>. Its uses in different aspects of inflammation and immune function are discussed, highlighting exercise-induced inflammation, mediating the effects of air pollution, and controlling thrombotic aspects of the immune response. Potential future developments in women’s health, erectile dysfunction, and the allergic response indicate how broad the utility of dietary antiplatelets can be. |
topic |
platelet function platelet activation platelet hyperactivity platelet-leukocyte aggregates inflammation immunothrombosis |
url |
https://www.mdpi.com/2072-6643/13/7/2184 |
work_keys_str_mv |
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