An Efficient Therapy Strategy under a Novel HIV Model

By incorporating the chemotherapy into a previous model describing the interaction of the immune system with the human immunodeficiency virus (HIV), this paper proposes a novel HIV virus spread model with control variables. Our goal is to maximize the number of healthy cells and, meanwhile, to minim...

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Bibliographic Details
Main Authors: Chunming Zhang, Xiaofan Yang, Wanping Liu, Lu-Xing Yang
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Discrete Dynamics in Nature and Society
Online Access:http://dx.doi.org/10.1155/2011/828509
Description
Summary:By incorporating the chemotherapy into a previous model describing the interaction of the immune system with the human immunodeficiency virus (HIV), this paper proposes a novel HIV virus spread model with control variables. Our goal is to maximize the number of healthy cells and, meanwhile, to minimize the cost of chemotherapy. In this context, the existence of an optimal control is proved. Experimental results show that, under this model, the spread of HIV virus can be controlled effectively.
ISSN:1026-0226
1607-887X