κ-Opioid receptor stimulation reduces palmitate-induced apoptosis via Akt/eNOS signaling pathway

κ-Opioid receptor stimulation reduces palmitate-induced apoptosis via Akt/eNOS signaling pathway

Abstract Background This study was designed to test the hypothesis that κ-opioid receptor (κ-OR) stimulation reduces palmitate-induced HUVECs apoptosis and to investigate its mechanisms. Methods HUVECs were subjected to sodium palmitate, apoptosis and cell viability were determined, HUVECs were trea...

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Bibliographic Details
Main Authors: Yan Cui, Na Feng, Xiaoming Gu, Feng Fu, Jun Li, Haitao Guo, Yali Liu, Shumiao Zhang, Juan Li, Yuanbo Wang, Min Jia, Lu Yang, Fuyang Zhang, Yuemin Wang, Rong Fan, Jianming Pei
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Lipids in Health and Disease
Subjects:
κ-Opioid receptor
Palmitate
Apoptosis
Akt
eNOS
Online Access:http://link.springer.com/article/10.1186/s12944-019-0989-4

Internet

http://link.springer.com/article/10.1186/s12944-019-0989-4

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