Hypoxia changes the expression of the epidermal growth factor (EGF) system in human hearts and cultured cardiomyocytes.

<h4>Background</h4>The epidermal growth factor (EGF) receptors HER2 and HER4 and the ligands HB-EGF and NRG1 are crucial for heart development. The purpose of our study was to investigate the role of the complete EGF system in relation to hypoxia of the heart.<h4>Methodology/princi...

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Bibliographic Details
Main Authors: Mathias Munk, Ashfaque Ahmed Memon, Jens Peter Goetze, Lars Bo Nielsen, Ebba Nexo, Boe Sandahl Sorensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22792252/pdf/?tool=EBI

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