Helicobacter pylori and gastric cancer
Introduction: Helicobacter pylori has been linked to the development of chronic atrophic gastritis, intestinal metaplasia, and dysplasia, lesions that can progress to gastric carcinoma. There is research showing that the eradication of this bacterium reduces the risk of histopathological progression...
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doaj-fd8ecfba25144b3eba42eb5900cd9a562021-01-01T18:56:42ZspaECIMEDRevista Cubana de Medicina Militar1561-30461561-30462020-10-01494e0200616e0200616304Helicobacter pylori and gastric cancerLudmila Martínez Leyva0Teresita de Jesús Montero González1Felipe Neri Piñol Jiménez2Amada Belquis Palomino Besada3Miguel González-Carbajal Pascual4Danay Días Morejón5HMC Dr. Carlos J. FinlayHMC Dr. Luis Días SotoCNCMAHMC Dr. Carlos J. FinlayHospital Clínico-quirúrgico Joaquín AlbarránHMC Dr. Carlos J. FinlayIntroduction: Helicobacter pylori has been linked to the development of chronic atrophic gastritis, intestinal metaplasia, and dysplasia, lesions that can progress to gastric carcinoma. There is research showing that the eradication of this bacterium reduces the risk of histopathological progression of preneoplastic lesions, except for intestinal metaplasia and dysplasia. A bibliographic review was made of the articles published in the Pubmed, Scielo, Medline and Cochrane data bases, related to the topic, belonging to authors dedicated to the study of this problem. Objective: To go deepen in the knowledge related to Helicobacter pylori infection and gastric cancer. Development: Adenocarcinoma is the most frequent gastric tumor and Helicobacter pylori is the main etiologic agent. In high-risk populations, gastric adenocarcinoma of the intestinal type is preceded by preneoplastic lesions (atrophy, intestinal metaplasia, and dysplasia) that progresses to invasive cancer. Conclusions: Helicobacter pylori favors gastric carcinogenesis, although there are other risk factors for the development of gastric cancer such as: family history, poor intake of fruits and vegetables, and low socioeconomic level.http://www.revmedmilitar.sld.cu/index.php/mil/article/view/616helicobacter pylorigastritis crónica atróficametaplasia intestinaldisplasiacarcinoma gástrico. |
collection |
DOAJ |
language |
Spanish |
format |
Article |
sources |
DOAJ |
author |
Ludmila Martínez Leyva Teresita de Jesús Montero González Felipe Neri Piñol Jiménez Amada Belquis Palomino Besada Miguel González-Carbajal Pascual Danay Días Morejón |
spellingShingle |
Ludmila Martínez Leyva Teresita de Jesús Montero González Felipe Neri Piñol Jiménez Amada Belquis Palomino Besada Miguel González-Carbajal Pascual Danay Días Morejón Helicobacter pylori and gastric cancer Revista Cubana de Medicina Militar helicobacter pylori gastritis crónica atrófica metaplasia intestinal displasia carcinoma gástrico. |
author_facet |
Ludmila Martínez Leyva Teresita de Jesús Montero González Felipe Neri Piñol Jiménez Amada Belquis Palomino Besada Miguel González-Carbajal Pascual Danay Días Morejón |
author_sort |
Ludmila Martínez Leyva |
title |
Helicobacter pylori and gastric cancer |
title_short |
Helicobacter pylori and gastric cancer |
title_full |
Helicobacter pylori and gastric cancer |
title_fullStr |
Helicobacter pylori and gastric cancer |
title_full_unstemmed |
Helicobacter pylori and gastric cancer |
title_sort |
helicobacter pylori and gastric cancer |
publisher |
ECIMED |
series |
Revista Cubana de Medicina Militar |
issn |
1561-3046 1561-3046 |
publishDate |
2020-10-01 |
description |
Introduction: Helicobacter pylori has been linked to the development of chronic atrophic gastritis, intestinal metaplasia, and dysplasia, lesions that can progress to gastric carcinoma. There is research showing that the eradication of this bacterium reduces the risk of histopathological progression of preneoplastic lesions, except for intestinal metaplasia and dysplasia. A bibliographic review was made of the articles published in the Pubmed, Scielo, Medline and Cochrane data bases, related to the topic, belonging to authors dedicated to the study of this problem.
Objective: To go deepen in the knowledge related to Helicobacter pylori infection and gastric cancer.
Development: Adenocarcinoma is the most frequent gastric tumor and Helicobacter pylori is the main etiologic agent. In high-risk populations, gastric adenocarcinoma of the intestinal type is preceded by preneoplastic lesions (atrophy, intestinal metaplasia, and dysplasia) that progresses to invasive cancer.
Conclusions: Helicobacter pylori favors gastric carcinogenesis, although there are other risk factors for the development of gastric cancer such as: family history, poor intake of fruits and vegetables, and low socioeconomic level. |
topic |
helicobacter pylori gastritis crónica atrófica metaplasia intestinal displasia carcinoma gástrico. |
url |
http://www.revmedmilitar.sld.cu/index.php/mil/article/view/616 |
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