Dynamics of free-radical processes in the animals after protracted influence of exogenous nitric oxide and ionizing radiation

Aim of the investigation was to study the influence of nitric oxide (NO) and low doses of ionizing radiation (LDIR) on free radical processes that occur in various tissues of mammalian organism. Fractionated LDIR irradia-tion was shown to temporarily disrupt an oxidative metabolism. At same time pro...

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Main Authors:	L. I. Makovetska, O. B. Ganzha, N. K. Rodionova, M. O. Druzhyna, V. M. Mikhailenko
Format:	Article
Language:	English
Published:	Institute for Nuclear Research, National Academy of Sciences of Ukraine 2012-12-01
Series:	Âderna Fìzika ta Energetika
Subjects:	low doses of ionizing radiation nitric oxide superoxide radical free radical processes antioxidative
Online Access:	http://jnpae.kinr.kiev.ua/13.4/Articles_PDF/jnpae-2012-13-0387-Makovetska.pdf

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spelling	doaj-fda6461640724d14a7ea186e6573e8902020-11-24T22:16:18ZengInstitute for Nuclear Research, National Academy of Sciences of UkraineÂderna Fìzika ta Energetika1818-331X2074-05652012-12-01134387391Dynamics of free-radical processes in the animals after protracted influence of exogenous nitric oxide and ionizing radiationL. I. Makovetska0O. B. Ganzha1N. K. Rodionova2M. O. Druzhyna3V. M. Mikhailenko4R. E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, Kyiv, UkraineR. E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, Kyiv, UkraineR. E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, Kyiv, UkraineR. E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, Kyiv, UkraineR. E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, Kyiv, UkraineAim of the investigation was to study the influence of nitric oxide (NO) and low doses of ionizing radiation (LDIR) on free radical processes that occur in various tissues of mammalian organism. Fractionated LDIR irradia-tion was shown to temporarily disrupt an oxidative metabolism. At same time protracted NO inhalation causes more significant harmful effects. This indicated that there are two pathways of oxidative metabolism disruption caused by generation of reactive oxygen or nitrogen species in tissues of mammalian organism.http://jnpae.kinr.kiev.ua/13.4/Articles_PDF/jnpae-2012-13-0387-Makovetska.pdflow doses of ionizing radiationnitric oxidesuperoxide radicalfree radical processesantioxidative
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	L. I. Makovetska O. B. Ganzha N. K. Rodionova M. O. Druzhyna V. M. Mikhailenko
spellingShingle	L. I. Makovetska O. B. Ganzha N. K. Rodionova M. O. Druzhyna V. M. Mikhailenko Dynamics of free-radical processes in the animals after protracted influence of exogenous nitric oxide and ionizing radiation Âderna Fìzika ta Energetika low doses of ionizing radiation nitric oxide superoxide radical free radical processes antioxidative
author_facet	L. I. Makovetska O. B. Ganzha N. K. Rodionova M. O. Druzhyna V. M. Mikhailenko
author_sort	L. I. Makovetska
title	Dynamics of free-radical processes in the animals after protracted influence of exogenous nitric oxide and ionizing radiation
title_short	Dynamics of free-radical processes in the animals after protracted influence of exogenous nitric oxide and ionizing radiation
title_full	Dynamics of free-radical processes in the animals after protracted influence of exogenous nitric oxide and ionizing radiation
title_fullStr	Dynamics of free-radical processes in the animals after protracted influence of exogenous nitric oxide and ionizing radiation
title_full_unstemmed	Dynamics of free-radical processes in the animals after protracted influence of exogenous nitric oxide and ionizing radiation
title_sort	dynamics of free-radical processes in the animals after protracted influence of exogenous nitric oxide and ionizing radiation
publisher	Institute for Nuclear Research, National Academy of Sciences of Ukraine
series	Âderna Fìzika ta Energetika
issn	1818-331X 2074-0565
publishDate	2012-12-01
description	Aim of the investigation was to study the influence of nitric oxide (NO) and low doses of ionizing radiation (LDIR) on free radical processes that occur in various tissues of mammalian organism. Fractionated LDIR irradia-tion was shown to temporarily disrupt an oxidative metabolism. At same time protracted NO inhalation causes more significant harmful effects. This indicated that there are two pathways of oxidative metabolism disruption caused by generation of reactive oxygen or nitrogen species in tissues of mammalian organism.
topic	low doses of ionizing radiation nitric oxide superoxide radical free radical processes antioxidative
url	http://jnpae.kinr.kiev.ua/13.4/Articles_PDF/jnpae-2012-13-0387-Makovetska.pdf
work_keys_str_mv	AT limakovetska dynamicsoffreeradicalprocessesintheanimalsafterprotractedinfluenceofexogenousnitricoxideandionizingradiation AT obganzha dynamicsoffreeradicalprocessesintheanimalsafterprotractedinfluenceofexogenousnitricoxideandionizingradiation AT nkrodionova dynamicsoffreeradicalprocessesintheanimalsafterprotractedinfluenceofexogenousnitricoxideandionizingradiation AT modruzhyna dynamicsoffreeradicalprocessesintheanimalsafterprotractedinfluenceofexogenousnitricoxideandionizingradiation AT vmmikhailenko dynamicsoffreeradicalprocessesintheanimalsafterprotractedinfluenceofexogenousnitricoxideandionizingradiation
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Dynamics of free-radical processes in the animals after protracted influence of exogenous nitric oxide and ionizing radiation

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