A comparative study of the capacity of mesenchymal stromal cell lines to form spheroids.

Mesenchymal stem cells (MSC)-spheroid models favor maintenance of stemness, ex vivo expansion and transplantation efficacy. Spheroids may also be considered as useful surrogate models of the hematopoietic niche. However, accessibility to primary cells, from bone marrow (BM) or adipose tissues, may l...

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Main Authors: Margaux Deynoux, Nicola Sunter, Elfi Ducrocq, Hassan Dakik, Roseline Guibon, Julien Burlaud-Gaillard, Lucie Brisson, Florence Rouleux-Bonnin, Louis-Romée le Nail, Olivier Hérault, Jorge Domenech, Philippe Roingeard, Gaëlle Fromont, Frédéric Mazurier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0225485