WNK1 Kinase Stimulates Angiogenesis to Promote Tumor Growth and Metastasis

WNK1 Kinase Stimulates Angiogenesis to Promote Tumor Growth and Metastasis

With-no-lysine (K)-1 (WNK1) is the founding member of family of four protein kinases with atypical placement of catalytic lysine that play important roles in regulating epithelial ion transport. Gain-of-function mutations of WNK1 and WNK4 cause a mendelian hypertension and hyperkalemic disease. WNK1...

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Bibliographic Details
Main Authors: Zong-Lin Sie, Ruei-Yang Li, Bonifasius Putera Sampurna, Po-Jui Hsu, Shu-Chen Liu, Horng-Dar Wang, Chou-Long Huang, Chiou-Hwa Yuh
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
with-no-lysine (k) kinase i
tumor-induced angiogenesis
zebrafish
hepatocellular carcinoma
colorectal cancer
Online Access:https://www.mdpi.com/2072-6694/12/3/575

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