Study on the chemical composition of Nauclea officinalis in different months of the same year and different growth years

• Main Authors: Yu-Xin Zhang, Jun- Qing Zhang, Xiao-Liang Li
• Format: Article
• Language: English
• Published: Editorial Board of Journal of Hainan Medical University 2021-06-01
• Series: Journal of Hainan Medical University
• Subjects: nauclea officinalis; different growth years; different months; active ingredient; lc-ms/ms
• Online Access: http://www.hnykdxxb.com/PDF/202112/09.pdf

Objective: Based on the quality analysis of Nauclea officinalis in different growth years and different months in the same year, the most suitable harvest year and the specific month in the same year were determined according to the evaluation of the active components in the stem of medicinal parts of Nauclea officinalis. Methods: LC-MS/MS method was used to investigate the quality of Nauclea officinalis from different growth years and different months in the same year, mainly including the content determination of the active ingredients in the medicine. Results: With the prolongation of production life, the content of active ingredients in stem of Nauclea officinalis increased continuously. After reaching a certain number of years, the content of active ingredients increased little;In the middle of the same year, from mid-October to mid- June of the next year, the content of iso-vincin lactam was relatively high, especially between the end of March and the end of May. The content was high and stable, and the highest point was the stem sample collected in May. Conclusion: The content of each component in the stem of Nauclea officinalis with a growth life of more than 5 years has reached a relatively high and stable level.Nauclea officinalis with a growth life of more than 5 years should be collected as raw materials for medicinal materials. The month with high and stable content of isocyanoside lactam, namely May of each year, was taken as the best harvest time of gallbladder in one year. The best harvest time was from mid-October to mid-June of the next year, or from March to May of each year.