Rapid perturbation in viremia levels drives increases in functional avidity of HIV-specific CD8 T cells.
The factors determining the functional avidity and its relationship with the broad heterogeneity of antiviral T cell responses remain partially understood. We investigated HIV-specific CD8 T cell responses in 85 patients with primary HIV infection (PHI) or chronic (progressive and non-progressive) i...
Main Authors: | Selena Viganò, Felicitas Bellutti Enders, Isabelle Miconnet, Cristina Cellerai, Anne-Laure Savoye, Virginie Rozot, Matthieu Perreau, Mohamed Faouzi, Khalid Ohmiti, Matthias Cavassini, Pierre-Alexandre Bart, Giuseppe Pantaleo, Alexandre Harari |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS Pathogens |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23853580/pdf/?tool=EBI |
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