Long-term radiotherapy related complications in children with head and neck cancer: Another era for pediatric oncologic pathology
Nikolaos Eleftheriadis2, Christos Papaloukas1, Damianos Eleftheriadis1, Apostolos Hatzitolios2, Ioulia Ioannidou-Marathiotou3, Kiki Pistevou-Gompaki11Department of Radiation, Oncology, AHEPA University Hospital; 2A’Propedeutic Department of Internal Medicine, AHEPA University Hospital;...
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2009-03-01
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doaj-fdced2ac9c1f4239a95297f1cda624c82020-11-25T00:53:22ZengDove Medical PressInternational Journal of General Medicine1178-70742009-03-012009default6366Long-term radiotherapy related complications in children with head and neck cancer: Another era for pediatric oncologic pathologyNikolaos EleftheriadisChristos PapaloukasDamianos EleftheriadisApostolos HatzitoliosIoulia Ioannidou-MarathiotouKiki Pistevou-GompakiNikolaos Eleftheriadis2, Christos Papaloukas1, Damianos Eleftheriadis1, Apostolos Hatzitolios2, Ioulia Ioannidou-Marathiotou3, Kiki Pistevou-Gompaki11Department of Radiation, Oncology, AHEPA University Hospital; 2A’Propedeutic Department of Internal Medicine, AHEPA University Hospital; 3Department of Orthodontics, School of Dentistry, Aristotle’s University of Thessaloniki, GreeceAbstract: Long-term radiotherapy-related complications in children with head and neck cancer have been frequently reported, especially facial growth disorders and dental abnormalities. We report on two male children (8 and 14 years old) with head and neck cancer, who were successfully treated with chemoradiotherapy and presented with growth deficiency of middle face and mandible hypoplasia, eight years and one year later, respectively. These severe growth complications attributed to chemoradiotherapy, while the patients survived primary malignancy. Patient age at irradiation was significantly correlated with the severity of disorders. We consider late sequelae in children with head and neck cancer due to chemoradiotherapy another era for pediatric oncologic pathology for prevention, if possible, or to manage them efficiently.Keywords: radiotherapy, head and neck cancer, growth disorders http://www.dovepress.com/long-term-radiotherapy-related-complications-in-children-with-head-and-a2997 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Nikolaos Eleftheriadis Christos Papaloukas Damianos Eleftheriadis Apostolos Hatzitolios Ioulia Ioannidou-Marathiotou Kiki Pistevou-Gompaki |
spellingShingle |
Nikolaos Eleftheriadis Christos Papaloukas Damianos Eleftheriadis Apostolos Hatzitolios Ioulia Ioannidou-Marathiotou Kiki Pistevou-Gompaki Long-term radiotherapy related complications in children with head and neck cancer: Another era for pediatric oncologic pathology International Journal of General Medicine |
author_facet |
Nikolaos Eleftheriadis Christos Papaloukas Damianos Eleftheriadis Apostolos Hatzitolios Ioulia Ioannidou-Marathiotou Kiki Pistevou-Gompaki |
author_sort |
Nikolaos Eleftheriadis |
title |
Long-term radiotherapy related complications in children with head and neck cancer: Another era for pediatric oncologic pathology |
title_short |
Long-term radiotherapy related complications in children with head and neck cancer: Another era for pediatric oncologic pathology |
title_full |
Long-term radiotherapy related complications in children with head and neck cancer: Another era for pediatric oncologic pathology |
title_fullStr |
Long-term radiotherapy related complications in children with head and neck cancer: Another era for pediatric oncologic pathology |
title_full_unstemmed |
Long-term radiotherapy related complications in children with head and neck cancer: Another era for pediatric oncologic pathology |
title_sort |
long-term radiotherapy related complications in children with head and neck cancer: another era for pediatric oncologic pathology |
publisher |
Dove Medical Press |
series |
International Journal of General Medicine |
issn |
1178-7074 |
publishDate |
2009-03-01 |
description |
Nikolaos Eleftheriadis2, Christos Papaloukas1, Damianos Eleftheriadis1, Apostolos Hatzitolios2, Ioulia Ioannidou-Marathiotou3, Kiki Pistevou-Gompaki11Department of Radiation, Oncology, AHEPA University Hospital; 2A’Propedeutic Department of Internal Medicine, AHEPA University Hospital; 3Department of Orthodontics, School of Dentistry, Aristotle’s University of Thessaloniki, GreeceAbstract: Long-term radiotherapy-related complications in children with head and neck cancer have been frequently reported, especially facial growth disorders and dental abnormalities. We report on two male children (8 and 14 years old) with head and neck cancer, who were successfully treated with chemoradiotherapy and presented with growth deficiency of middle face and mandible hypoplasia, eight years and one year later, respectively. These severe growth complications attributed to chemoradiotherapy, while the patients survived primary malignancy. Patient age at irradiation was significantly correlated with the severity of disorders. We consider late sequelae in children with head and neck cancer due to chemoradiotherapy another era for pediatric oncologic pathology for prevention, if possible, or to manage them efficiently.Keywords: radiotherapy, head and neck cancer, growth disorders |
url |
http://www.dovepress.com/long-term-radiotherapy-related-complications-in-children-with-head-and-a2997 |
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