Compound A Increases Cell Infiltration in Target Organs of Acute Graft-versus-Host Disease (aGVHD) in a Mouse Model

Compound A Increases Cell Infiltration in Target Organs of Acute Graft-versus-Host Disease (aGVHD) in a Mouse Model

Systemic steroids are used to treat acute graft-versus-host disease (aGVHD) caused by allogenic bone marrow transplantation (allo-BMT); however, their prolonged use results in complications. Hence, new agents for treating aGVHD are required. Recently, a new compound A (CpdA), with anti-inflammatory...

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Bibliographic Details
Main Authors: Abdellatif Bouazzaoui, Ahmed A. H. Abdellatif, Faisal A. Al-Allaf, Neda M. Bogari, Mohiuddin M. Taher, Mohammad Athar, Thomas Schubert, Turki M. Habeebullah, Sameer H. Qari
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
stem cell transplantation
graft-versus-host disease
compound A
bioactive compounds
T cells
cytokines
Online Access:https://www.mdpi.com/1420-3049/26/14/4237

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