Epidemiology of antenatal depression in Africa: a systematic review and meta-analysis
Abstract Background Antenatal depression is a serious problem worldwide that has devastating consequences not only for the mother but also for the child and family. The pooled evidence regarding the prevalence and associated factors of antenatal depression is rare in Africa. Hence this review aimed...
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doaj-fdcfe6c001414df6bb3409aa302b67822020-11-25T02:02:36ZengBMCBMC Pregnancy and Childbirth1471-23932020-04-0120111310.1186/s12884-020-02929-5Epidemiology of antenatal depression in Africa: a systematic review and meta-analysisAbel Fekadu Dadi0Haileab Fekadu Wolde1Adhanom Gebreegziabher Baraki2Temesgen Yihunie Akalu3University of Gondar, College of Medicine and Health Sciences, Institute of Public Health, Department of Epidemiology and BiostatisticsUniversity of Gondar, College of Medicine and Health Sciences, Institute of Public Health, Department of Epidemiology and BiostatisticsUniversity of Gondar, College of Medicine and Health Sciences, Institute of Public Health, Department of Epidemiology and BiostatisticsUniversity of Gondar, College of Medicine and Health Sciences, Institute of Public Health, Department of Epidemiology and BiostatisticsAbstract Background Antenatal depression is a serious problem worldwide that has devastating consequences not only for the mother but also for the child and family. The pooled evidence regarding the prevalence and associated factors of antenatal depression is rare in Africa. Hence this review aimed to investigate the prevalence and associated factors of antenatal depression in Africa. Methods We searched CINHAL, MEDLINE, PsycINFO, Psychiatry online, PubMed, SCOPES, and Emcare databases for English written observational studies conducted in Africa from 2007 to 2018.Quality of studies was assessed using the Newcastle Ottawa Scale (NOS), and studies with good quality were included in the final review. Heterogeneity across studies was assessed using the I 2 and Higgins test. Publication bias was checked using Funnel plot symmetry, and Egger’s regression test and adjustment was made by using Duval and Tweedie’s Trim and Fill analysis. A random effect Meta-analysis was employed to determine the pooled estimates with 95% confidence interval (CI). Stata 14 was used for analysis. The review protocol has been registered in PROSPERO number CRD42018106717. Result Of the 175 studies identified, 28 studies with an overall sample size of 17,938 were included. According to the random effect model following trim and fill analysis, the pooled prevalence of antenatal depression in Africa was 26.3% (95%CI: 22.2, 30.4%). Economic difficulties [POR = 1.87;95%CI:1.25,2.78,I 2 = 88.1%], unfavorable marital condition [POR = 4.17;95% CI:1.75, 9.94, I 2 = 81.2%], poor support from relatives [POR = 1.36;95% CI:1.18, 1.56, I 2 = 78.0%], bad obstetric history [POR = 2.30;95% CI:1.81, 2.92), I 2 = 81.7%], and history of mental health problem [POR = 2.97; 95% CI:1.74, 5.06, I 2 = 92.0%]were the factors associated with antenatal depression. Conclusion The prevalence of antenatal depression is high in Africa, which showed that one in four pregnant women had depression. Pregnant mothers who had economic difficulties, bad obstetric history, poor support from relatives, previous mental health problems, and unfavorable marital conditions were at higher risk of antenatal depression. Therefore these factors should be considered while designing mental health care services for pregnant mothers.http://link.springer.com/article/10.1186/s12884-020-02929-5Antenatal depressionAssociated factorsSystematic reviewMeta-analysisAfrica |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Abel Fekadu Dadi Haileab Fekadu Wolde Adhanom Gebreegziabher Baraki Temesgen Yihunie Akalu |
spellingShingle |
Abel Fekadu Dadi Haileab Fekadu Wolde Adhanom Gebreegziabher Baraki Temesgen Yihunie Akalu Epidemiology of antenatal depression in Africa: a systematic review and meta-analysis BMC Pregnancy and Childbirth Antenatal depression Associated factors Systematic review Meta-analysis Africa |
author_facet |
Abel Fekadu Dadi Haileab Fekadu Wolde Adhanom Gebreegziabher Baraki Temesgen Yihunie Akalu |
author_sort |
Abel Fekadu Dadi |
title |
Epidemiology of antenatal depression in Africa: a systematic review and meta-analysis |
title_short |
Epidemiology of antenatal depression in Africa: a systematic review and meta-analysis |
title_full |
Epidemiology of antenatal depression in Africa: a systematic review and meta-analysis |
title_fullStr |
Epidemiology of antenatal depression in Africa: a systematic review and meta-analysis |
title_full_unstemmed |
Epidemiology of antenatal depression in Africa: a systematic review and meta-analysis |
title_sort |
epidemiology of antenatal depression in africa: a systematic review and meta-analysis |
publisher |
BMC |
series |
BMC Pregnancy and Childbirth |
issn |
1471-2393 |
publishDate |
2020-04-01 |
description |
Abstract Background Antenatal depression is a serious problem worldwide that has devastating consequences not only for the mother but also for the child and family. The pooled evidence regarding the prevalence and associated factors of antenatal depression is rare in Africa. Hence this review aimed to investigate the prevalence and associated factors of antenatal depression in Africa. Methods We searched CINHAL, MEDLINE, PsycINFO, Psychiatry online, PubMed, SCOPES, and Emcare databases for English written observational studies conducted in Africa from 2007 to 2018.Quality of studies was assessed using the Newcastle Ottawa Scale (NOS), and studies with good quality were included in the final review. Heterogeneity across studies was assessed using the I 2 and Higgins test. Publication bias was checked using Funnel plot symmetry, and Egger’s regression test and adjustment was made by using Duval and Tweedie’s Trim and Fill analysis. A random effect Meta-analysis was employed to determine the pooled estimates with 95% confidence interval (CI). Stata 14 was used for analysis. The review protocol has been registered in PROSPERO number CRD42018106717. Result Of the 175 studies identified, 28 studies with an overall sample size of 17,938 were included. According to the random effect model following trim and fill analysis, the pooled prevalence of antenatal depression in Africa was 26.3% (95%CI: 22.2, 30.4%). Economic difficulties [POR = 1.87;95%CI:1.25,2.78,I 2 = 88.1%], unfavorable marital condition [POR = 4.17;95% CI:1.75, 9.94, I 2 = 81.2%], poor support from relatives [POR = 1.36;95% CI:1.18, 1.56, I 2 = 78.0%], bad obstetric history [POR = 2.30;95% CI:1.81, 2.92), I 2 = 81.7%], and history of mental health problem [POR = 2.97; 95% CI:1.74, 5.06, I 2 = 92.0%]were the factors associated with antenatal depression. Conclusion The prevalence of antenatal depression is high in Africa, which showed that one in four pregnant women had depression. Pregnant mothers who had economic difficulties, bad obstetric history, poor support from relatives, previous mental health problems, and unfavorable marital conditions were at higher risk of antenatal depression. Therefore these factors should be considered while designing mental health care services for pregnant mothers. |
topic |
Antenatal depression Associated factors Systematic review Meta-analysis Africa |
url |
http://link.springer.com/article/10.1186/s12884-020-02929-5 |
work_keys_str_mv |
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