A 54-Year-Old Woman with Donor Cell Origin of Multiple Myeloma after Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of CML

A 54-Year-Old Woman with Donor Cell Origin of Multiple Myeloma after Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of CML

Chronic myeloid leukemia is a myeloproliferative disorder that may be treated with hematopoietic stem cell transplantation (HSCT). While posttransplantation relapse of disease resulting from a failure to eradicate the patient’s original leukemia could occur, patients may also rarely develop a second...

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Main Authors: Erika Maestas, Shikha Jain, Patrick Stiff
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2016/6751914
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spelling doaj-fdd55d2f5e164837a4a84b086a20a1d22020-11-25T01:05:36ZengHindawi LimitedCase Reports in Hematology2090-65602090-65792016-01-01201610.1155/2016/67519146751914A 54-Year-Old Woman with Donor Cell Origin of Multiple Myeloma after Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of CMLErika Maestas0Shikha Jain1Patrick Stiff2Loyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USALoyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USALoyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USAChronic myeloid leukemia is a myeloproliferative disorder that may be treated with hematopoietic stem cell transplantation (HSCT). While posttransplantation relapse of disease resulting from a failure to eradicate the patient’s original leukemia could occur, patients may also rarely develop a secondary malignancy or myelodysplastic syndrome (MDS) of donor origin termed donor cell leukemia (DCL). Cases of donor-derived acute myeloid leukemia (AML) or MDS after HSCT or solid tumor transplantation have been published. However, very few cases of donor-derived multiple myeloma (MM) exist. We describe a patient who developed a donor-derived MM following allogeneic HSCT from a sibling donor.http://dx.doi.org/10.1155/2016/6751914
collection DOAJ
language English
format Article
sources DOAJ
author Erika Maestas
Shikha Jain
Patrick Stiff
spellingShingle Erika Maestas
Shikha Jain
Patrick Stiff
A 54-Year-Old Woman with Donor Cell Origin of Multiple Myeloma after Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of CML
Case Reports in Hematology
author_facet Erika Maestas
Shikha Jain
Patrick Stiff
author_sort Erika Maestas
title A 54-Year-Old Woman with Donor Cell Origin of Multiple Myeloma after Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of CML
title_short A 54-Year-Old Woman with Donor Cell Origin of Multiple Myeloma after Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of CML
title_full A 54-Year-Old Woman with Donor Cell Origin of Multiple Myeloma after Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of CML
title_fullStr A 54-Year-Old Woman with Donor Cell Origin of Multiple Myeloma after Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of CML
title_full_unstemmed A 54-Year-Old Woman with Donor Cell Origin of Multiple Myeloma after Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of CML
title_sort 54-year-old woman with donor cell origin of multiple myeloma after allogeneic hematopoietic stem cell transplantation for the treatment of cml
publisher Hindawi Limited
series Case Reports in Hematology
issn 2090-6560
2090-6579
publishDate 2016-01-01
description Chronic myeloid leukemia is a myeloproliferative disorder that may be treated with hematopoietic stem cell transplantation (HSCT). While posttransplantation relapse of disease resulting from a failure to eradicate the patient’s original leukemia could occur, patients may also rarely develop a secondary malignancy or myelodysplastic syndrome (MDS) of donor origin termed donor cell leukemia (DCL). Cases of donor-derived acute myeloid leukemia (AML) or MDS after HSCT or solid tumor transplantation have been published. However, very few cases of donor-derived multiple myeloma (MM) exist. We describe a patient who developed a donor-derived MM following allogeneic HSCT from a sibling donor.
url http://dx.doi.org/10.1155/2016/6751914
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AT shikhajain a54yearoldwomanwithdonorcelloriginofmultiplemyelomaafterallogeneichematopoieticstemcelltransplantationforthetreatmentofcml
AT patrickstiff a54yearoldwomanwithdonorcelloriginofmultiplemyelomaafterallogeneichematopoieticstemcelltransplantationforthetreatmentofcml
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AT shikhajain 54yearoldwomanwithdonorcelloriginofmultiplemyelomaafterallogeneichematopoieticstemcelltransplantationforthetreatmentofcml
AT patrickstiff 54yearoldwomanwithdonorcelloriginofmultiplemyelomaafterallogeneichematopoieticstemcelltransplantationforthetreatmentofcml
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