Clonotypic Analysis of Immunoglobulin Heavy Chain Sequences in Patients with Waldenström’s Macroglobulinemia: Correlation with MYD88 L265P Somatic Mutation Status, Clinical Features, and Outcome
We performed IGH clonotypic sequence analysis in WM in order to determine whether a preferential IGH gene rearrangement was observed and to assess IGHV mutational status in blood and/or bone marrow samples from 36 WM patients. In addition we investigated the presence of MYD88 L265P somatic mutation....
Main Authors: | Loizos Petrikkos, Marie-Christine Kyrtsonis, Maria Roumelioti, George Georgiou, Anna Efthymiou, Tatiana Tzenou, Panayiotis Panayiotidis |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2014-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2014/809103 |
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