The ULK1/2 and AMPK Inhibitor SBI-0206965 Blocks AICAR and Insulin-Stimulated Glucose Transport

The ULK1/2 and AMPK Inhibitor SBI-0206965 Blocks AICAR and Insulin-Stimulated Glucose Transport

The small molecule kinase inhibitor SBI-0206965 was originally described as a specific inhibitor of ULK1/2. More recently, it was reported to effectively inhibit AMPK and several studies now report its use as an AMPK inhibitor. Currently, we investigated the specificity of SBI-0206965 in incubated m...

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Bibliographic Details
Main Authors: Jonas R. Knudsen, Agnete B. Madsen, Kaspar W. Persson, Carlos Henríquez-Olguín, Zhencheng Li, Thomas E. Jensen
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:International Journal of Molecular Sciences
Subjects:
AMPK
ULK1/2
skeletal muscle
kinase inhibitor
SBI-0206965
Online Access:https://www.mdpi.com/1422-0067/21/7/2344

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