Mass Spectrometric Determination of the Effect of Surface Deactivation on Membranes Used for In-Situ Sampling of Cerebrospinal Fluid (CSF)

Mass Spectrometric Determination of the Effect of Surface Deactivation on Membranes Used for In-Situ Sampling of Cerebrospinal Fluid (CSF)

In this paper, a strategy for structured monitoring of surface modifications to control protein adsorption to membrane structures is presented. The already established on-surface enzymatic digestion (oSED) method combined with nano-liquid chromatography and tandem mass spectrometry (LC-MS/MS) analys...

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Bibliographic Details
Main Authors: Torgny Undin, Andreas P. Dahlin, Jonas Bergquist, Sara Bergström Lind
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Separations
Subjects:
protein adsorption
surface modification
Pluronic F-127
LC MS/MS
Online Access:http://www.mdpi.com/2297-8739/5/2/27

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