Screening for thalassemia and other hemoglobinopathies in a tertiary care hospital of West Bengal: Implications for population screening
Hemoglobinopathies are common genetic disorders of hemoglobin, which can be prevented by population screening and offering genetic counseling. In absence of population-based screening for hemoglobinopathies, the hospital-based diagnosis register provide idea about the extent of problem in the commun...
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Wolters Kluwer Medknow Publications
2012-01-01
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doaj-fe150c786b504fa5b16dd448b4d07d7e2020-11-24T21:44:28ZengWolters Kluwer Medknow PublicationsIndian Journal of Public Health0019-557X2012-01-0156429730010.4103/0019-557X.106419Screening for thalassemia and other hemoglobinopathies in a tertiary care hospital of West Bengal: Implications for population screeningBhawna Bhutoria JainRabindra Nath RoySulekha GhoshTapan GhoshUma BanerjeeSubodh Kumar BhattacharyaHemoglobinopathies are common genetic disorders of hemoglobin, which can be prevented by population screening and offering genetic counseling. In absence of population-based screening for hemoglobinopathies, the hospital-based diagnosis register provide idea about the extent of problem in the community. The present study was undertaken to find out the burden of hemoglobinopathies and spectrum of this disorders among the population who were screened in the hospital-based screening program. A record-basedanalysis of subjects who underwent screening for hemoglobinopathies in Burdwan Medical College and Hospital over a period of 3 years and 4 months revealed that overall 29.3% of subjects were positive for hemoglobinopathies. Beta thalassemia heterozygous was the most commonhemoglobinopathy in this region closely followed by hemoglobin E heterozygous. In view of high prevalence of hemoglobinopathies in this region, a routine premarital screening program is needed for identification and prevention of high-risk marriages.http://www.ijph.in/article.asp?issn=0019-557X;year=2012;volume=56;issue=4;spage=297;epage=300;aulast=JainCarrier screeningHemoglobinopathiesThalassaemia |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Bhawna Bhutoria Jain Rabindra Nath Roy Sulekha Ghosh Tapan Ghosh Uma Banerjee Subodh Kumar Bhattacharya |
spellingShingle |
Bhawna Bhutoria Jain Rabindra Nath Roy Sulekha Ghosh Tapan Ghosh Uma Banerjee Subodh Kumar Bhattacharya Screening for thalassemia and other hemoglobinopathies in a tertiary care hospital of West Bengal: Implications for population screening Indian Journal of Public Health Carrier screening Hemoglobinopathies Thalassaemia |
author_facet |
Bhawna Bhutoria Jain Rabindra Nath Roy Sulekha Ghosh Tapan Ghosh Uma Banerjee Subodh Kumar Bhattacharya |
author_sort |
Bhawna Bhutoria Jain |
title |
Screening for thalassemia and other hemoglobinopathies in a tertiary care hospital of West Bengal: Implications for population screening |
title_short |
Screening for thalassemia and other hemoglobinopathies in a tertiary care hospital of West Bengal: Implications for population screening |
title_full |
Screening for thalassemia and other hemoglobinopathies in a tertiary care hospital of West Bengal: Implications for population screening |
title_fullStr |
Screening for thalassemia and other hemoglobinopathies in a tertiary care hospital of West Bengal: Implications for population screening |
title_full_unstemmed |
Screening for thalassemia and other hemoglobinopathies in a tertiary care hospital of West Bengal: Implications for population screening |
title_sort |
screening for thalassemia and other hemoglobinopathies in a tertiary care hospital of west bengal: implications for population screening |
publisher |
Wolters Kluwer Medknow Publications |
series |
Indian Journal of Public Health |
issn |
0019-557X |
publishDate |
2012-01-01 |
description |
Hemoglobinopathies are common genetic disorders of hemoglobin, which can be prevented by population screening and offering genetic counseling. In absence of population-based screening for hemoglobinopathies, the hospital-based diagnosis register provide idea about the extent of problem in the community. The present study was undertaken to find out the burden of hemoglobinopathies and spectrum of this disorders among the population who were screened in the hospital-based screening program. A record-basedanalysis of subjects who underwent screening for hemoglobinopathies in Burdwan Medical College and Hospital over a period of 3 years and 4 months revealed that overall 29.3% of subjects were positive for hemoglobinopathies. Beta thalassemia heterozygous was the most commonhemoglobinopathy in this region closely followed by hemoglobin E heterozygous. In view of high prevalence of hemoglobinopathies in this region, a routine premarital screening program is needed for identification and prevention of high-risk marriages. |
topic |
Carrier screening Hemoglobinopathies Thalassaemia |
url |
http://www.ijph.in/article.asp?issn=0019-557X;year=2012;volume=56;issue=4;spage=297;epage=300;aulast=Jain |
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