Castleman`s Disease and POEMS Syndrome: case reporte and review of literature
Castleman’s disease is a lymphoproliferative disorder related with human herpesvirus 8 and HIV, presenting in two different ways. The unicentric form is benign, doesn’t have systemic symptoms and is usually cured with surgery. The multicentric form usually presents with generalized lymphadenopathy,...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Hospital de Clinicas de Porto Alegre ; Universidade Federal do Rio Grande do Sul (UFRGS)
2008-08-01
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| Series: | Clinical and Biomedical Research |
| Subjects: | |
| Online Access: | http://seer.ufrgs.br/index.php/hcpa/article/view/3976 |
| Summary: | Castleman’s disease is a lymphoproliferative disorder related with human herpesvirus 8 and HIV, presenting in two different ways. The unicentric form is benign, doesn’t have systemic symptoms and is usually cured with surgery. The multicentric form usually presents with generalized lymphadenopathy, fever, weight loss, and other systemic manifestations and it can be associated with malignancy, especially POEMS syndrome. We report a case of a 50 year old man presenting with weight loss, fever and lymphadenopathy, associated with monoclonal gammopathy, organomegaly, endocrinopathy and neuropathy, which diagnosis was Castleman’s disease with POEMS syndrome |
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| ISSN: | 0101-5575 2357-9730 |