Cleavage of the vaspin N-terminus releases cell-penetrating peptides that affect early stages of adipogenesis and inhibit lipolysis in mature adipocytes

Vaspin expression and function is related to metabolic disorders and comorbidities of obesity. In various cellular and animal models of obesity, diabetes and atherosclerosis vaspin has shown beneficial, protective and/or compensatory action. While testing proteases for inhibition by vaspin, we notic...

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Bibliographic Details
Main Authors: Catherine A. Tindall, Estelle Erkner, Jan Stichel, Annette G. Beck-Sickinger, Anne Hoffmann, Juliane Weiner, John T. Heiker
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Adipocyte
Subjects:
Online Access:http://dx.doi.org/10.1080/21623945.2021.1910154