Pediatric hereditary angioedema: an update [version 1; referees: 2 approved]

Pediatric hereditary angioedema: an update [version 1; referees: 2 approved]

Hereditary angioedema (HAE) with C1-inhibitor (C1-Inh) deficiency (C1-Inh-HAE) is a rare, life-threatening, and disabling genetic disorder characterized by self-limited tissue swelling caused by deficiency or dysfunction of C1-Inh. Our aim in this update is to discuss new advances in HAE therapy, fo...

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Main Authors: Geetika Sabharwal, Timothy Craig
Format: Article
Language:English
Published: F1000 Research Ltd 2017-07-01
Series:F1000Research
Subjects:
Clinical Immunology
Endocrine & Metabolic Pharmacology
Immunopharmacology & Hematologic Pharmacology
Innate Immunity
Medical Genetics
Pediatric Hematology
Online Access:https://f1000research.com/articles/6-1205/v1
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spelling doaj-fe3d743497894ac2be1953b7d362aff22020-11-25T03:50:53ZengF1000 Research LtdF1000Research2046-14022017-07-01610.12688/f1000research.11320.112217Pediatric hereditary angioedema: an update [version 1; referees: 2 approved]Geetika Sabharwal0Timothy Craig1Division of Pulmonary, Allergy and Critical Care, Department of Allergy and Immunology, Penn State University, Milton S. Hershey Medical Center, Hershey, PA, USADivision of Pulmonary, Allergy and Critical Care, Department of Allergy and Immunology, Penn State University, Milton S. Hershey Medical Center, Hershey, PA, USAHereditary angioedema (HAE) with C1-inhibitor (C1-Inh) deficiency (C1-Inh-HAE) is a rare, life-threatening, and disabling genetic disorder characterized by self-limited tissue swelling caused by deficiency or dysfunction of C1-Inh. Our aim in this update is to discuss new advances in HAE therapy, focusing mainly on the various treatment options that have become available recently and also drugs that are under trial for prophylaxis to prevent attacks. There is a paradigm shift to where the treatment of HAE is headed, focusing now on prophylactic treatment rather than abortive management.https://f1000research.com/articles/6-1205/v1Clinical ImmunologyEndocrine & Metabolic PharmacologyImmunopharmacology & Hematologic PharmacologyInnate ImmunityMedical GeneticsPediatric Hematology
collection DOAJ
language English
format Article
sources DOAJ
author Geetika Sabharwal
Timothy Craig
spellingShingle Geetika Sabharwal
Timothy Craig
Pediatric hereditary angioedema: an update [version 1; referees: 2 approved]
F1000Research
Clinical Immunology
Endocrine & Metabolic Pharmacology
Immunopharmacology & Hematologic Pharmacology
Innate Immunity
Medical Genetics
Pediatric Hematology
author_facet Geetika Sabharwal
Timothy Craig
author_sort Geetika Sabharwal
title Pediatric hereditary angioedema: an update [version 1; referees: 2 approved]
title_short Pediatric hereditary angioedema: an update [version 1; referees: 2 approved]
title_full Pediatric hereditary angioedema: an update [version 1; referees: 2 approved]
title_fullStr Pediatric hereditary angioedema: an update [version 1; referees: 2 approved]
title_full_unstemmed Pediatric hereditary angioedema: an update [version 1; referees: 2 approved]
title_sort pediatric hereditary angioedema: an update [version 1; referees: 2 approved]
publisher F1000 Research Ltd
series F1000Research
issn 2046-1402
publishDate 2017-07-01
description Hereditary angioedema (HAE) with C1-inhibitor (C1-Inh) deficiency (C1-Inh-HAE) is a rare, life-threatening, and disabling genetic disorder characterized by self-limited tissue swelling caused by deficiency or dysfunction of C1-Inh. Our aim in this update is to discuss new advances in HAE therapy, focusing mainly on the various treatment options that have become available recently and also drugs that are under trial for prophylaxis to prevent attacks. There is a paradigm shift to where the treatment of HAE is headed, focusing now on prophylactic treatment rather than abortive management.
topic Clinical Immunology
Endocrine & Metabolic Pharmacology
Immunopharmacology & Hematologic Pharmacology
Innate Immunity
Medical Genetics
Pediatric Hematology
url https://f1000research.com/articles/6-1205/v1
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AT timothycraig pediatrichereditaryangioedemaanupdateversion1referees2approved
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