Transcription factor 7-like 2 (TCF7L2) variant is associated with familial breast cancer risk: a case-control study

Transcription factor 7-like 2 (TCF7L2) variant is associated with familial breast cancer risk: a case-control study

<p>Abstract</p> <p>Background</p> <p>The transcription factor 7-like 2 (TCF7L2) is a critical component of the Wnt/β-catenin pathway. Aberrant <it>TCF7L2 </it>expression modifies Wnt signaling and mediates oncogenic effects through the upregulation of <it...

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Bibliographic Details
Main Authors: Schmutzler Rita K, Meindl Alfons, Hemminki Kari, Shanmugam Kalai S, Burwinkel Barbara, Sutter Christian, Wappenschmidt Barbara, Kiechle Marion, Bartram Claus R, Frank Bernd
Format: Article
Language:English
Published: BMC 2006-11-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/6/268

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