Study on sEng, VEGF, PLGF, and sFlt-1 levels, and umbilical artery blood flow change in the pregnant women with preeclampsia
Objective: To observe sEng, VEGF, PLGF, and sFlt-1 levels, and umbilical artery blood flow change in the pregnant women with preeclampsia (PE), and their clinical significance. Methods: A total of 60 pregnant women with moderate and severe PE who were admitted in our hospital from January, 2014 to...
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doaj-fe551526b309416fbcad35b72327aa732020-11-25T00:35:42ZengEditorial Board of Journal of Hainan Medical UniversityJournal of Hainan Medical University1007-12371007-12372016-04-012284951Study on sEng, VEGF, PLGF, and sFlt-1 levels, and umbilical artery blood flow change in the pregnant women with preeclampsiaXia Liu0The Maternal and Child Care Center of Shijiazhuang City in Hebei Province, 050000Objective: To observe sEng, VEGF, PLGF, and sFlt-1 levels, and umbilical artery blood flow change in the pregnant women with preeclampsia (PE), and their clinical significance. Methods: A total of 60 pregnant women with moderate and severe PE who were admitted in our hospital from January, 2014 to April, 2015 were included in the study and divided into the observation group 1 and observation group 2 with 30 cases in each group. ELISA was used to detect the levels of serum sEng, VEGF, PLGF, and sFlt-1. The color Doppler Ultrasound Diagnosis Apparatus was used to detect the changes of S/D, and RI. A total of 30 pregnant women who came for antenatal examination at the same period were served as the control group. Results:The levels of serum sEng, and sFlt-1 in the observation group 1 and 2 were significantly higher than those in the control group. The levels of serum sEng, and sFlt-1 in the observation group 2 were significantly higher than those in the observation group 1. The levels of serum VEGF and PLGF in the observation group 1 and 2 were significantly lower than those in the control group. The levels of serum VEGF and PLGF in the observation group were significantly lower than those in the observation group 1. S/D, and RI in the observation group 1 and 2 were significantly higher than those in the control group. S/D, and RI in the observation group 2 were significantly higher than those in the observation group 1. Conclusions: The serum sEng, VEGF, PLGF, and sFlt-1 levels are associated with PE, detection of which can accurately estimate the severity degree of PE, and determination of the umbilical artery blood flow can also accurately reflect PE condition.http://www.hnykdxxb.com/PDF/201608/14.pdfPEsEngVEGFsFlt-1PLGFUmbilical artery blood flow |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Xia Liu |
spellingShingle |
Xia Liu Study on sEng, VEGF, PLGF, and sFlt-1 levels, and umbilical artery blood flow change in the pregnant women with preeclampsia Journal of Hainan Medical University PE sEng VEGF sFlt-1 PLGF Umbilical artery blood flow |
author_facet |
Xia Liu |
author_sort |
Xia Liu |
title |
Study on sEng, VEGF, PLGF, and sFlt-1 levels, and umbilical artery blood flow change in the pregnant women with preeclampsia |
title_short |
Study on sEng, VEGF, PLGF, and sFlt-1 levels, and umbilical artery blood flow change in the pregnant women with preeclampsia |
title_full |
Study on sEng, VEGF, PLGF, and sFlt-1 levels, and umbilical artery blood flow change in the pregnant women with preeclampsia |
title_fullStr |
Study on sEng, VEGF, PLGF, and sFlt-1 levels, and umbilical artery blood flow change in the pregnant women with preeclampsia |
title_full_unstemmed |
Study on sEng, VEGF, PLGF, and sFlt-1 levels, and umbilical artery blood flow change in the pregnant women with preeclampsia |
title_sort |
study on seng, vegf, plgf, and sflt-1 levels, and umbilical artery blood flow change in the pregnant women with preeclampsia |
publisher |
Editorial Board of Journal of Hainan Medical University |
series |
Journal of Hainan Medical University |
issn |
1007-1237 1007-1237 |
publishDate |
2016-04-01 |
description |
Objective: To observe sEng, VEGF, PLGF, and sFlt-1 levels, and umbilical artery blood flow change in the pregnant women with preeclampsia (PE), and their clinical significance. Methods: A total of 60 pregnant women with moderate and severe PE who
were admitted in our hospital from January, 2014 to April, 2015 were included in the study and divided into the observation group 1 and observation group 2 with 30 cases in each group. ELISA was used to detect the levels of serum sEng, VEGF, PLGF, and sFlt-1. The color Doppler Ultrasound Diagnosis Apparatus was used to detect the changes of S/D, and RI. A total of 30 pregnant women who came for antenatal examination at the same period were served as the control group. Results:The levels of serum sEng, and sFlt-1 in the observation group 1 and 2 were significantly higher than those in the control group. The levels of serum sEng,
and sFlt-1 in the observation group 2 were significantly higher than those in the observation group 1. The levels of serum VEGF and PLGF in the observation group 1 and 2 were significantly lower than those in the control group. The levels of serum VEGF and PLGF in the observation group were significantly lower than those in the observation group 1. S/D, and RI in the observation group 1 and 2 were significantly higher than those in the control group.
S/D, and RI in the observation group 2 were significantly higher than those in the observation group 1. Conclusions: The serum sEng, VEGF, PLGF, and sFlt-1 levels are associated with
PE, detection of which can accurately estimate the severity degree of PE, and determination of the umbilical artery blood flow can also accurately reflect PE condition. |
topic |
PE sEng VEGF sFlt-1 PLGF Umbilical artery blood flow |
url |
http://www.hnykdxxb.com/PDF/201608/14.pdf |
work_keys_str_mv |
AT xialiu studyonsengvegfplgfandsflt1levelsandumbilicalarterybloodflowchangeinthepregnantwomenwithpreeclampsia |
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