18FDG positron emission tomography mining for metabolic imaging biomarkers of radiation-induced xerostomia in patients with oropharyngeal cancer

18FDG positron emission tomography mining for metabolic imaging biomarkers of radiation-induced xerostomia in patients with oropharyngeal cancer

Purpose: Head and neck cancers radiotherapy (RT) is associated with inevitable injury to parotid glands and subsequent xerostomia. We investigated the utility of SUV derived from 18FDG-PET to develop metabolic imaging biomarkers (MIBs) of RT-related parotid injury. Methods: Data for oropharyngeal ca...

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Bibliographic Details
Main Authors: Hesham Elhalawani, Carlos E. Cardenas, Stefania Volpe, Souptik Barua, Sonja Stieb, Calvin B. Rock, Timothy Lin, Pei Yang, Haijun Wu, Jhankruti Zaveri, Baher Elgohari, Lamiaa E. Abdallah, Amit Jethanandani, Abdallah S.R. Mohamed, Laurence E. Court, Katherine A. Hutcheson, G. Brandon Gunn, David I. Rosenthal, Steven J. Frank, Adam S. Garden, Arvind Rao, Clifton D. Fuller
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Clinical and Translational Radiation Oncology
Subjects:
Xerostomia
FDG-PET
Radiotherapy
Imaging biomarkers
Predictive model
Head and neck cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630821000550

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