Side effects of medical therapy for chronic hepatitis C
The treatment of chronic hepatitis C virus (HCV) has improved greatly over the past decade. Over half of all patients treated with the combination of peginterferon and ribavirin have the opportunity to achieve sustained virologic response. The major factors which interfere with this goal are the sid...
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2004-01-01
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doaj-fe70932d8fca491fa529d3cc2ca6f0ff2021-06-08T04:36:44ZengElsevierAnnals of Hepatology1665-26812004-01-0131510Side effects of medical therapy for chronic hepatitis CShiffman Mitchell L, MD0Hepatology Section, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA; Address for correspondence:The treatment of chronic hepatitis C virus (HCV) has improved greatly over the past decade. Over half of all patients treated with the combination of peginterferon and ribavirin have the opportunity to achieve sustained virologic response. The major factors which interfere with this goal are the side effects of therapy which require that the doses of peginterferon or ribavirin be reduced or that these medications be discontinued. While some of these side effects can be overcome and treatment continued, some side effects are severe and potentially life threatening. Appropriate recognition and management of these side effects will both improve response to therapy and avoid unnecessary morbidity and mortality.http://www.sciencedirect.com/science/article/pii/S1665268119321180Hepatitis C viruspeginterferon ribavirin side effects |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Shiffman Mitchell L, MD |
spellingShingle |
Shiffman Mitchell L, MD Side effects of medical therapy for chronic hepatitis C Annals of Hepatology Hepatitis C virus peginterferon ribavirin side effects |
author_facet |
Shiffman Mitchell L, MD |
author_sort |
Shiffman Mitchell L, MD |
title |
Side effects of medical therapy for chronic hepatitis C |
title_short |
Side effects of medical therapy for chronic hepatitis C |
title_full |
Side effects of medical therapy for chronic hepatitis C |
title_fullStr |
Side effects of medical therapy for chronic hepatitis C |
title_full_unstemmed |
Side effects of medical therapy for chronic hepatitis C |
title_sort |
side effects of medical therapy for chronic hepatitis c |
publisher |
Elsevier |
series |
Annals of Hepatology |
issn |
1665-2681 |
publishDate |
2004-01-01 |
description |
The treatment of chronic hepatitis C virus (HCV) has improved greatly over the past decade. Over half of all patients treated with the combination of peginterferon and ribavirin have the opportunity to achieve sustained virologic response. The major factors which interfere with this goal are the side effects of therapy which require that the doses of peginterferon or ribavirin be reduced or that these medications be discontinued. While some of these side effects can be overcome and treatment continued, some side effects are severe and potentially life threatening. Appropriate recognition and management of these side effects will both improve response to therapy and avoid unnecessary morbidity and mortality. |
topic |
Hepatitis C virus peginterferon ribavirin side effects |
url |
http://www.sciencedirect.com/science/article/pii/S1665268119321180 |
work_keys_str_mv |
AT shiffmanmitchelllmd sideeffectsofmedicaltherapyforchronichepatitisc |
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