Tissue specific changes in acyl-CoA: cholesterol acyltransferase (ACAT) mRNA levels in rabbits.

Tissue specific changes in acyl-CoA: cholesterol acyltransferase (ACAT) mRNA levels in rabbits.

A human cDNA clone (K1) was recently isolated that encodes functional acyl-CoA:cholesterol acyltransferase (ACAT) protein (Chang et al. J. Biol. Chem. 1993. 268: 20747-20755). We used the K1 clone to screen a rabbit liver cDNA library and isolated a 919 base pair partial rabbit cDNA (ACAT14b) that w...

Full description

Bibliographic Details
Main Authors:	M E Pape, P A Schultz, T J Rea, R B DeMattos, K Kieft, C L Bisgaier, R S Newton, B R Krause
Format:	Article
Language:	English
Published:	Elsevier 1995-04-01
Series:	Journal of Lipid Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520400665

Similar Items

Assessment of acyl-CoA cholesterol acyltransferase (ACAT-1) role in ovarian cancer progression-An in vitro study.
by: Vijayalakshmi N Ayyagari, et al.
Published: (2020-01-01)

ACBP and cholesterol differentially alter fatty acyl CoA utilization by microsomal ACAT
by: Hsu Chao, et al.
Published: (2003-01-01)

Role of acyl-CoA: cholesterol acyltransferase in cellular cholesterol metabolism.
by: K E Suckling, et al.
Published: (1985-06-01)

Acyl-Coenzyme A: Cholesterol Acyltransferase (ACAT) in Cholesterol Metabolism: From Its Discovery to Clinical Trials and the Genomics Era
by: Qimin Hai, et al.
Published: (2021-08-01)

The sterol substrate specificity of acyl CoA: :cholesterol acyltransferase from rat liver.
by: D M Tavani, et al.
Published: (1982-07-01)

Characterisation of sunflower lysophosphpatidylcholine Acyl-CoA acyltransferase
by: Fraser, Thomas Colin Michael
Published: (1994)

beta-sitosterol: esterification by intestinal acylcoenzyme A: cholesterol acyltransferase (ACAT) and its effect on cholesterol esterification
by: F J Field, et al.
Published: (1983-04-01)

In vivo evidence that the lipid-regulating activity of the ACAT inhibitor CI-976 in rats is due to inhibition of both intestinal and liver ACAT.
by: BR Krause, et al.
Published: (1993-02-01)

The role of carnitine acyltransferases in plant acyl CoA metabolism
by: Wood, C.
Published: (1984)

Recent progress on acyl CoA: lysophospholipid acyltransferase research
by: Hideo Shindou, et al.
Published: (2009-01-01)

Regulation of hepatic cholesterol ester hydrolase and acyl-coenzyme A:cholesterol acyltransferase in the rat.
by: B G Stone, et al.
Published: (1989-11-01)

The microsomal cardiolipin remodeling enzyme acyl-CoA lysocardiolipin acyltransferase is an acyltransferase of multiple anionic lysophospholipids
by: Yang Zhao, et al.
Published: (2009-05-01)

Tissue expression studies on the mouse acyl-CoA: cholesterol acyltransferase gene (Acact): findings supporting the existence of multiple cholesterol esterification enzymes in mice
by: V Meiner, et al.
Published: (1997-09-01)

Cholesterol absorption in rat intestine: role of cholesterol esterase and acyl coenzyme A:cholesterol acyltransferase.
by: L L Gallo, et al.
Published: (1984-06-01)

Modulation Peroxisome Proliferators Activated Receptor alpha (PPAR α) and Acyl Coenzyme A: Cholesterol Acyltransferase1 (ACAT1) Gene expression by Fatty Acids in Foam cell
by: Mojarrad Majed, et al.
Published: (2009-09-01)

Modulation Peroxisome Proliferators Activated Receptor alpha (PPAR α) and Acyl Coenzyme A: Cholesterol Acyltransferase1 (ACAT1) Gene expression by Fatty Acids in Foam cell
by: Packnejad Malehieh, et al.
Published: (2009-10-01)

Inhibition of acyl-CoA: cholesterol acyltransferase decreases apolipoprotein B-100-containing lipoprotein secretion from HepG2 cells.
by: R Musanti, et al.
Published: (1996-01-01)

Role of acyl CoA:cholesterol acyltransferase in cholesterol absorption and its inhibition by 57-118 in the rabbit.
by: J G Heider, et al.
Published: (1983-09-01)

Allosteric modulation of the substrate specificity of acyl-CoA wax alcohol acyltransferase 2
by: Jason M. Arne, et al.
Published: (2017-04-01)

Rabbit liver apolipoprotein A-I synthesis is under nonparenchymal cell paracrine control.
by: T J Rea, et al.
Published: (1994-07-01)

Studies on acyl-coenzyme A: cholesterol acyltransferase activity in human liver microsomes.
by: K Einarsson, et al.
Published: (1989-05-01)

Hepatic acyl-coenzyme A:cholesterol acyltransferase activity is decreased in patients with cholesterol gallstones.
by: JL Smith, et al.
Published: (1990-11-01)

Molecular characterization of two type I acyl-CoA: diacylglycerol acyltransferase genes in maize
by: Qingzhi Li, et al.
Published: (2016-05-01)

Immunodepletion experiments suggest that acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT-1) protein plays a major catalytic role in adult human liver, adrenal gland, macrophages, and kidney, but not in intestines
by: Oneil Lee, et al.
Published: (1998-08-01)

Normal cholesterol absorption in rats deficient in intestinal acyl coenzyme A:cholesterol acyltransferase activity
by: L L Gallo, et al.
Published: (1987-04-01)

Influence of membrane environment and pharmacological agents on acyl CoA:cholesterol acyltransferase
by: Harte, Rachel A.
Published: (1994)

Reduced cholesterol transmucosal transport in rats with inhibited mucosal acyl CoA:cholesterol acyltransferase and normal pancreatic function.
by: S B Clark, et al.
Published: (1984-02-01)

Functional Characterization of Lysophosphatidylcholine: Acyl-CoA Acyltransferase Genes From Sunflower (Helianthus annuus L.)
by: Ana Mapelli-Brahm, et al.
Published: (2020-04-01)

Molecular Characterization of Two Lysophospholipid:acyl-CoA Acyltransferases Belonging to the MBOAT Family in Nicotiana benthamiana.
by: Donghui Zhang, et al.
Published: (2015-01-01)

Regulation of acyl CoA:cholesterol acyltransferase by 25-hydroxycholesterol in rabbit intestinal microsomes and absorptive cells.
by: F J Field, et al.
Published: (1983-08-01)

Role of the intestinal acyl-CoA:cholesterol acyltransferase activity in the hyperresponse of diabetic rats to dietary cholesterol.
by: P Maechler, et al.
Published: (1992-10-01)

Acyl-CoA wax alcohol acyltransferase 2: its regulation and actions in support of color vision1
by: William S. Blaner
Published: (2017-04-01)

Evolutionary view of acyl-CoA diacylglycerol acyltransferase (DGAT), a key enzyme in neutral lipid biosynthesis
by: Margis-Pinheiro Marcia, et al.
Published: (2011-09-01)

Acyl-CoA:cholesterol acyltransferase in human small intestine: its activity and some properties of the enzymic reaction.
by: P Helgerud, et al.
Published: (1981-02-01)

Identification of potential substrate-binding sites in yeast and human acyl-CoA sterol acyltransferases by mutagenesis of conserved sequences
by: Zhongmin Guo, et al.
Published: (2001-08-01)

The ontogeny of acyl coenzyme A: cholesterol acyltransferase in rat liver, intestine, adipose tissue, and aorta
by: Little, Marie-Térèse E.
Published: (2010)

Amino acids 149 and 294 of human lecithin:cholesterol acyltransferase affect fatty acyl specificity
by: Yue Zhao, et al.
Published: (2004-12-01)

Acyl-coenzyme A:cholesterol acyltransferase promotes oxidized LDL/oxysterol-induced apoptosis in macrophages
by: Natalie E. Freeman, et al.
Published: (2005-09-01)

Molecular species of phosphatidylcholine in abetalipoproteinemia: effect of lecithin:cholesterol acyltransferase and lysolecithin acyltransferase.
by: B Banerji, et al.
Published: (1989-12-01)

Regulation of HMG-CoA reductase, HSL and ACAT expression and activity in testicular cholesterol metabolism in mink and in mouse following experimental genetic deletion
by: Chen, Li
Published: (2010)