Causes of treatment failure for hepatitis C in the era of direct-acting antiviral therapy

Causes of treatment failure for hepatitis C in the era of direct-acting antiviral therapy

Hepatitis C therapy in the era of the newer direct-acting antiviral agents has radically changed our treatment schemes by achieving very high rates of sustained virological response. However, treatment with direct antiviral agents fails in a subgroup of patients. This group of so-called difficult-to...

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Main Authors: Joaquín Cabezas, Susana Llerena, Ángela Puente, Emilio Fábrega, Javier Crespo
Format: Article
Language:English
Published: Aran Ediciones
Series:Revista Espanola de Enfermedades Digestivas
Subjects:
Hepatitis C
Agentes antivirales de acción directa
Fracaso de la terapia
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082016000700007&lng=en&tlng=en
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spelling doaj-fea6ebaaeee0448cbfbc1e9f8d1af8532020-11-24T20:42:48ZengAran EdicionesRevista Espanola de Enfermedades Digestivas1130-0108108742143010.17235/reed.2015.3894/2015S1130-01082016000700007Causes of treatment failure for hepatitis C in the era of direct-acting antiviral therapyJoaquín Cabezas0Susana Llerena1Ángela Puente2Emilio Fábrega3Javier Crespo4Hospital Universitario Marqués de ValdecillaHospital Universitario Marqués de ValdecillaHospital Universitario Marqués de ValdecillaHospital Universitario Marqués de ValdecillaHospital Universitario Marqués de ValdecillaHepatitis C therapy in the era of the newer direct-acting antiviral agents has radically changed our treatment schemes by achieving very high rates of sustained virological response. However, treatment with direct antiviral agents fails in a subgroup of patients. This group of so-called difficult-to-treat individuals is the subject of this paper, which reviews the causes of virological failure, their clinical implications, and some final recommendations.http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082016000700007&lng=en&tlng=enHepatitis CAgentes antivirales de acción directaFracaso de la terapia
collection DOAJ
language English
format Article
sources DOAJ
author Joaquín Cabezas
Susana Llerena
Ángela Puente
Emilio Fábrega
Javier Crespo
spellingShingle Joaquín Cabezas
Susana Llerena
Ángela Puente
Emilio Fábrega
Javier Crespo
Causes of treatment failure for hepatitis C in the era of direct-acting antiviral therapy
Revista Espanola de Enfermedades Digestivas
Hepatitis C
Agentes antivirales de acción directa
Fracaso de la terapia
author_facet Joaquín Cabezas
Susana Llerena
Ángela Puente
Emilio Fábrega
Javier Crespo
author_sort Joaquín Cabezas
title Causes of treatment failure for hepatitis C in the era of direct-acting antiviral therapy
title_short Causes of treatment failure for hepatitis C in the era of direct-acting antiviral therapy
title_full Causes of treatment failure for hepatitis C in the era of direct-acting antiviral therapy
title_fullStr Causes of treatment failure for hepatitis C in the era of direct-acting antiviral therapy
title_full_unstemmed Causes of treatment failure for hepatitis C in the era of direct-acting antiviral therapy
title_sort causes of treatment failure for hepatitis c in the era of direct-acting antiviral therapy
publisher Aran Ediciones
series Revista Espanola de Enfermedades Digestivas
issn 1130-0108
description Hepatitis C therapy in the era of the newer direct-acting antiviral agents has radically changed our treatment schemes by achieving very high rates of sustained virological response. However, treatment with direct antiviral agents fails in a subgroup of patients. This group of so-called difficult-to-treat individuals is the subject of this paper, which reviews the causes of virological failure, their clinical implications, and some final recommendations.
topic Hepatitis C
Agentes antivirales de acción directa
Fracaso de la terapia
url http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082016000700007&lng=en&tlng=en
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AT susanallerena causesoftreatmentfailureforhepatitiscintheeraofdirectactingantiviraltherapy
AT angelapuente causesoftreatmentfailureforhepatitiscintheeraofdirectactingantiviraltherapy
AT emiliofabrega causesoftreatmentfailureforhepatitiscintheeraofdirectactingantiviraltherapy
AT javiercrespo causesoftreatmentfailureforhepatitiscintheeraofdirectactingantiviraltherapy
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